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https://hdl.handle.net/2440/88505
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Type: | Journal article |
Title: | Effectiveness of electronic fetal monitoring with additional ST analysis in vertex singleton pregnancies at >36 weeks of gestation: an individual participant data metaanalysis |
Author: | Schuit, E. Amer-Wahlin, I. Ojala, K. Vayssiere, C. Westerhuis, M. Marsal, K. Tekay, A. Saade, G. Visser, G. Groenwold, R. Moons, K. Mol, B. Kwee, A. |
Citation: | American Journal of Obstetrics and Gynecology, 2013; 208(3):187.e1-187.e13 |
Publisher: | Mosby |
Issue Date: | 2013 |
ISSN: | 0002-9378 1097-6868 |
Statement of Responsibility: | Ewoud Schuit, Isis Amer-Wahlin, Kati Ojala, Christophe Vayssière, Michelle E.M.H. Westerhuis, Karel Maršál, Aydin Tekay, George R. Saade, Gerard H.A. Visser, Rolf H.H. Groenwold, Karel G.M. Moons, Ben Willem J. Mol, Anneke Kwee |
Abstract: | OBJECTIVE: The purpose of this study was to assess the effectiveness of electronic fetal monitoring (EFM) alone and with additional ST analysis (EFM+ST) in laboring women with a singleton term pregnancy that is in cephalic presentation in the prevention of metabolic acidosis by the application of individual patient data metaanalysis. STUDY DESIGN: We conducted an individual patient data metaanalysis using data from 4 randomized trials, which enabled us to account for missing data and investigate relevant subgroups. The primary outcome was metabolic acidosis, which was defined as an umbilical cord-artery pH <7.05 and a base deficit that had been calculated in the extra cellular fluid compartment >12 mmol/L. We performed 8 explanatory subgroup analyses for 8 different endpoints. RESULTS: We analyzed data from 12,987 women and their newborn infants. Metabolic acidosis was present in 57 women (0.9%) in the EFM+ST group and 73 women (1.1%) in the EFM alone group (relative risk [RR], 0.76; 95% CI, 0.53–1.10). Compared with EFM alone, the use of EFM+ST resulted in a reduction in the frequency of instrumental vaginal deliveries (RR, 0.90; 95% CI, 0.83– 0.99) and fetal blood samples (RR, 0.49; 95% CI, 0.44–0.55). Cesarean delivery rates were comparable between both groups (RR, 0.99; 95% CI, 0.91–1.09). Subgroup analyses showed that EFM+ST resulted in fewer admissions to a neonatal intensive care unit for women with a duration of pregnancy of +41 weeks (RR, 0.61; 95% CI, 0.39–0.95). CONCLUSION: EFM+ST does not reduce the risk of metabolic acidosis, but it does reduce the need for instrumental vaginal deliveries and fetal blood sampling. |
Keywords: | Cardiotocography; fetal blood sampling; fetal electrocardiogram; instrumental vaginal delivery; metabolic acidosis |
Rights: | © 2013 Mosby, Inc. All rights reserved. |
DOI: | 10.1016/j.ajog.2013.01.028 |
Published version: | http://dx.doi.org/10.1016/j.ajog.2013.01.028 |
Appears in Collections: | Aurora harvest 7 Paediatrics publications |
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