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|dc.identifier.citation||Journal of Physiology, 1997; 503(Part 2):455-462||en|
|dc.description.abstract||1. Gastric mechanics were investigated by categorizing the temporal and spatial patterning of pressure waves associated with individual gastric contractions. 2. In twelve healthy volunteers, intraluminal pressures were monitored from nine side hole recording points spaced at 1.5 cm intervals along the antrum, pylorus and duodenum. 3. Pressure wave sequences that occurred during phase II fasting contractions (n = 221) and after food (n = 778) were evaluated. 4. The most common pattern of pressure wave onset along the antrum was a variable combination of antegrade, synchronous and retrograde propagation between side hole pairs. This variable pattern accounted for 42% of sequences after food, and 34% during fasting (P < 0.05). Other common pressure wave sequence patterns were: purely antegrade-29% after food and 42% during fasting (P < 0.05); purely synchronous-23% fed and 17% fasting; and purely retrograde-6% fed and 8% fasting. The length of sequences was shorter after food (P < 0.05). Some sequences 'skipped' individual recording points. 5. The spatial patterning of gastric pressure wave sequences is diverse, and may explain the differing mechanical outcomes among individual gastric contractions. 6. Better understanding of gastric mechanics may be gained from temporally precise correlations of luminal flows and pressures and gastric wall motion during individual gastric contraction sequences.||en|
|dc.description.statementofresponsibility||W. M. Sun, G. S. Hebbard, C.-H. Malbert, K. L. Jones, S. Doran, M. Horowitz and J. Dent||en|
|dc.publisher||CAMBRIDGE UNIV PRESS||en|
|dc.subject||Duodenum; Stomach; Pyloric Antrum; Pylorus; Humans; Fasting; Postprandial Period; Pressure; Time Factors; Adult; Middle Aged; Female; Male||en|
|dc.title||Spatial patterns of fasting and fed antropyloric pressure waves in humans.||en|
|dc.identifier.orcid||Malbert, C. [0000-0002-0665-4545]||en|
|dc.identifier.orcid||Jones, K. [0000-0002-1155-5816]||en|
|dc.identifier.orcid||Horowitz, M. [0000-0002-0942-0306]||en|
|Appears in Collections:||Medicine publications|
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