Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/9019
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dc.contributor.authorSun, W.en
dc.contributor.authorHebbard, G.en
dc.contributor.authorMalbert, C.en
dc.contributor.authorJones, K.en
dc.contributor.authorDoran, S.en
dc.contributor.authorHorowitz, M.en
dc.contributor.authorDent, J.en
dc.date.issued1997en
dc.identifier.citationJournal of Physiology, 1997; 503(Part 2):455-462en
dc.identifier.issn0022-3751en
dc.identifier.issn1469-7793en
dc.identifier.urihttp://hdl.handle.net/2440/9019-
dc.description.abstract1. Gastric mechanics were investigated by categorizing the temporal and spatial patterning of pressure waves associated with individual gastric contractions. 2. In twelve healthy volunteers, intraluminal pressures were monitored from nine side hole recording points spaced at 1.5 cm intervals along the antrum, pylorus and duodenum. 3. Pressure wave sequences that occurred during phase II fasting contractions (n = 221) and after food (n = 778) were evaluated. 4. The most common pattern of pressure wave onset along the antrum was a variable combination of antegrade, synchronous and retrograde propagation between side hole pairs. This variable pattern accounted for 42% of sequences after food, and 34% during fasting (P < 0.05). Other common pressure wave sequence patterns were: purely antegrade-29% after food and 42% during fasting (P < 0.05); purely synchronous-23% fed and 17% fasting; and purely retrograde-6% fed and 8% fasting. The length of sequences was shorter after food (P < 0.05). Some sequences 'skipped' individual recording points. 5. The spatial patterning of gastric pressure wave sequences is diverse, and may explain the differing mechanical outcomes among individual gastric contractions. 6. Better understanding of gastric mechanics may be gained from temporally precise correlations of luminal flows and pressures and gastric wall motion during individual gastric contraction sequences.en
dc.description.statementofresponsibilityW. M. Sun, G. S. Hebbard, C.-H. Malbert, K. L. Jones, S. Doran, M. Horowitz and J. Denten
dc.language.isoenen
dc.publisherCAMBRIDGE UNIV PRESSen
dc.subjectDuodenum; Stomach; Pyloric Antrum; Pylorus; Humans; Fasting; Postprandial Period; Pressure; Time Factors; Adult; Middle Aged; Female; Maleen
dc.titleSpatial patterns of fasting and fed antropyloric pressure waves in humans.en
dc.typeJournal articleen
dc.identifier.rmid0030004840en
dc.identifier.doi10.1111/j.1469-7793.1997.455bh.xen
dc.identifier.pubid68846-
pubs.library.collectionMedicine publicationsen
pubs.verification-statusVerifieden
pubs.publication-statusPublisheden
dc.identifier.orcidMalbert, C. [0000-0002-0665-4545]en
dc.identifier.orcidJones, K. [0000-0002-1155-5816]en
dc.identifier.orcidHorowitz, M. [0000-0002-0942-0306]en
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