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https://hdl.handle.net/2440/9096
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dc.contributor.author | Omari, T. | - |
dc.contributor.author | Bakewell, M. | - |
dc.contributor.author | Fraser, R. | - |
dc.contributor.author | Malbert, C.H. | - |
dc.contributor.author | Davidson, G. | - |
dc.contributor.author | Dent, J. | - |
dc.date.issued | 1996 | - |
dc.identifier.citation | Neurogastroenterology and Motility, 1996; 8(3):241-245 | - |
dc.identifier.issn | 1350-1925 | - |
dc.identifier.issn | 1365-2982 | - |
dc.identifier.uri | http://hdl.handle.net/2440/9096 | - |
dc.description.abstract | Conventional manometric techniques are unsuitable for studies in premature infants and small laboratory animals. We have therefore developed silicone rubber 5-lumen and 10-lumen micromanometric extrusions with an o.d. 2.0 mm and lumina of 0.35 mm i.d. This study evaluates the suitability of microextrusions for intraluminal perfusion manometry. Pressure offset, post-occlusion pressure rise rate and sphincter model studies were used to assess the manometric performance of the extrusions and a miniature sleeve sensor (25 mm long) at infusion rates of 0.01-0.1 mL min-1. Micro-extrusions (5-lumen/10-lumen, respectively) had offsets (per 100 cm of length) of 3.8/5.0 mmHg at 0.01 mL min-1 and 25.6/26.2 mmHg at 0.1 mL min-1 and rise rates (in 160 cm lengths) of 64/43 mmHg sec-1 at 0.01 mL min-1 and 330/224 mmHg sec-1 at 0.1 mL min-1. Infusion rates 0.025 mL min-1 produced rise rates 100 mmHg sec-1. The miniature sleeve sensor had minimal resistance to perfusion, rise rates of 3 mmHg sec-1 at 0.01 mL min-1 and 23 mmHg sec-1 at 0.1 mL min-1 and recorded pressure as accurately as a side hole. We conclude that the performance of micromanometric extrusions and sleeves is sufficient for intraluminal perfusion manometry. | - |
dc.description.statementofresponsibility | Omari, T. ; Bakewell, M. ; Fraser, R. ; Malbert, C. ; Davidson, G. ; Dent, J. | - |
dc.language.iso | en | - |
dc.publisher | BLACKWELL SCIENCE LTD | - |
dc.rights | ©1996 Blackwell Science Ltd | - |
dc.source.uri | http://dx.doi.org/10.1111/j.1365-2982.1996.tb00263.x | - |
dc.subject | Micromanometry | - |
dc.subject | Microextrusion | - |
dc.subject | Sleeve Sensor | - |
dc.subject | Rise Rate | - |
dc.subject | Fidelity | - |
dc.title | Intraluminal micromanometry: an evaluation of the dynamic performance of micro-extrusions and sleeve sensors | - |
dc.type | Journal article | - |
dc.identifier.doi | 10.1111/j.1365-2982.1996.tb00263.x | - |
pubs.publication-status | Published | - |
dc.identifier.orcid | Omari, T. [0000-0001-5108-7378] | - |
dc.identifier.orcid | Malbert, C.H. [0000-0002-0665-4545] | - |
Appears in Collections: | Aurora harvest 4 Medicine publications |
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