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|Title:||Development and validation of the Diabetes Bowel Symptom Questionnaire|
|Citation:||Alimentary Pharmacology & Therapeutics, 2003; 17(9):1179-1187|
|Publisher:||Blackwell Science Ltd|
|C. Quan, N. J. Talley, S. Cross, M. Jones, J. Hammer, N. Giles & M. Horowitz|
|Abstract:||Background: Although gastrointestinal symptoms occur frequently, there is no validated measure of gastrointestinal symptoms in patients with diabetes mellitus. Aim: To develop the Diabetes Bowel Symptom Questionnaire. Methods: A questionnaire derived from previously validated symptom measures was compiled to assess all relevant gastrointestinal and diabetes items. Face and content validity were ascertained by expert review. One hundred and sixty-eight patients with diabetes mellitus completed the instrument, and reliability was evaluated by a test–re-test procedure 1 week later. Concurrent validity was evaluated by an independent physician interview (n = 33). Measures of glycaemic control (glycated haemoglobin and plasma glucose) were compared with self-reported glycaemic control on a five-point Likert scale in diabetic out-patients (n = 166). Results: The questionnaire had adequate face and content validity. There was good to excellent test–re-test reliability for the gastrointestinal and diabetes items (median kappa: 0.63 and 0.79, respectively); concurrent validity was good to excellent (median kappa: 0.47 and 0.65, respectively), except for the items assessing the severity of gastrointestinal symptoms. Both glycated haemoglobin (P < 0.0001) and plasma glucose (P = 0.005) correlated significantly with self-reported glycaemic control. Conclusion: The Diabetes Bowel Symptom Questionnaire appears to be a useful measure of gastrointestinal symptoms and glycaemic control in diabetes mellitus, and should have applicability in epidemiological and clinical studies.|
|Keywords:||Humans; Gastrointestinal Diseases; Diabetes Complications; Sensitivity and Specificity; Reproducibility of Results; Adult; Aged; Middle Aged; Female; Male; Surveys and Questionnaires|
|Description:||The definitive version is available at www.blackwell-synergy.com Article first published online: 2 MAY 2003|
|Rights:||© 2003 Blackwell Publishing Ltd|
|Appears in Collections:||Medicine publications|
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