Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/92748
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Type: Journal article
Title: Transabdominal amnioinfusion for improving fetal outcomes after oligohydramnios secondary to preterm prelabour rupture of membranes before 26 weeks
Author: van Teeffelen, S.
Pajkrt, E.
Willekes, C.
van Kuijk, S.
Mol, B.
Citation: The Cochrane Database of Systematic Reviews, 2013; 2013(8):1-14
Publisher: Wiley
Issue Date: 2013
ISSN: 1469-493X
1469-493X
Statement of
Responsibility: 
Stijn Van Teeffelen, Eva Pajkrt, Christine Willekes, Sander MJ Van Kuijk, Ben Willem J Mol
Abstract: BACKGROUND Preterm prelabour rupture of membranes (PPROM) before 26 weeks can delay lung development and can cause pulmonary hypoplasia, as a result of oligohydramnios. Restoring the amniotic fluid volume by transabdominal amnioinfusion might prevent abnormal lung development and might have a protective effect for neurological complications, fetal deformities and neonatal sepsis. OBJECTIVES To assess the effectiveness of transabdominal amnioinfusion in improving perinatal outcome in women with oligohydramnios secondary to rupture of fetal membranes before 26 weeks. SEARCH METHODS We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (30 April 2013). SELECTION CRITERIA All randomised controlled trials comparing transabdominal amnioinfusion with no transabdominal amnioinfusion. Cluster- or quasi-randomised trials were not eligible for inclusion. In cases where only an abstract was available, we attempted to find the full articles. DATA COLLECTION AND ANALYSIS Two review authors assessed trials for inclusion. No eligible trials were identified. MAIN RESULTS There are no included studies. AUTHORS' CONCLUSIONS There is currently no evidence to evaluate the use of transabdominal amnioinfusion in women with oligohydramnios secondary to rupture of fetal membranes before 26 weeks for improving perinatal outcome. Further research examining the effects of this intervention is needed. Two randomised controlled trials are ongoing but final data have not yet been published.
Keywords: Lung; Amnion; Humans; Lung Diseases; Fetal Membranes, Premature Rupture; Oligohydramnios; Abnormalities, Multiple; Fluid Therapy; Infusions, Parenteral; Gestational Age; Pregnancy; Female; Obstetric Labor, Premature
Rights: Copyright © 2013 The Cochrane Collaboration.
RMID: 0020136981
DOI: 10.1002/14651858.CD009952.pub2
Appears in Collections:Paediatrics publications

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