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Type: Journal article
Title: Successful salvage of RAEB/AML relapsing early post allograft with FLAG-Ida conditioned mini-allograft: a report of two cases
Author: Hui, C.
Bardy, P.
Hughes, T.
Horvath, N.
To, L.
Citation: International Journal of Laboratory Hematology, 2001; 23(2):135-138
Publisher: Blackwell Publishing Ltd
Issue Date: 2001
ISSN: 1751-5521
Statement of
C.H. Hui, P. Bardy, T. Hughes, N. Horvath, L.B. To
Abstract: Management options are often limited for patients with AML or high grade myelodysplasia (MDS) relapsing within a year of allogeneic transplantation. We report, in two such patients, the use of re-induction with FLAG-Ida chemotherapy, followed by the infusion of GCSF-mobilized blood stem cells from the same HLA-matched donor. Both patients achieved durable complete remissions with good quality of life and longer disease-free survival than after the first myeloablative allografts. This mini-allograft approach offers a practical, well-tolerated salvage and a potentially curative treatment for relapsed AML/high grade MDS patients failing a first conventional myeloablative allogeneic transplants.
Keywords: Humans
Anemia, Refractory, with Excess of Blasts
Granulocyte Colony-Stimulating Factor
Recombinant Proteins
Antineoplastic Combined Chemotherapy Protocols
Salvage Therapy
Hematopoietic Stem Cell Transplantation
Transplantation, Homologous
Middle Aged
Leukemia, Myeloid, Acute
Description: The definitive version may be found at
Provenance: Published Online: 20 Dec 2001
Rights: Copyright © 2001 Blackwell Science Limited
DOI: 10.1046/j.1365-2257.2001.00359.x
Appears in Collections:Aurora harvest 4
Medicine publications

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