Please use this identifier to cite or link to this item: http://hdl.handle.net/2440/94816
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Type: Journal article
Title: Understanding the evolution of multimorbidity: evidences from the North West Adelaide Health Longitudinal Study (NWAHS)
Author: Ruel, G.
Lévesque, J.
Stocks, N.
Sirois, C.
Kroger, E.
Adams, R.
Doucet, M.
Taylor, A.
Citation: PLoS One, 2014; 9(5):e96291-1-e96291-11
Publisher: Public Library of Science
Issue Date: 2014
ISSN: 1932-6203
1932-6203
Statement of
Responsibility: 
Guillaume Ruel, Jean-Frédéric Lévesque, Nigel Stocks, Caroline Sirois, Edeltraut Kroger, Robert J. Adams, Mariève Doucet, Anne W. Taylor
Abstract: OBJECTIVE: The aim of this study is to describe the evolution of multimorbidity. STUDY DESIGN AND SETTING: Data from 1854 South Australians who participated in the North West Adelaide longitudinal Health Study (NWAHS) was collected between baseline (2000-2002) and follow-up (2008-2010). Status for eight chronic diseases (CDs) was determined by biomedical measurement or self-report. Chronic disease (CD) mean age of occurrence and order of appearance was investigated. RESULTS: The prevalence of multimorbidity increased from 32% to 64% during the 7.8±1.1 years of follow-up. The estimated mean age of onset of a new CD was significantly older for hypertension, cardiovascular disease (CVD) and chronic obstructive pulmonary disease (COPD) and younger for hypercholesterolemia, asthma and other mental problem. Hypercholesterolemia was more likely to develop as a first than as a subsequent CD (39%vs.16%, p<0.0001) while CVD (1%vs.5%, p<0.0001), diabetes (5%vs.11%, p<0.001) and COPD (6%vs.16%, p<0.0001) were less likely. The presence of mood disorders at baseline was associated with an increased risk of developing other mental disorders (36%vs.12%, p<0.0001), diabetes (18%vs.9%, p<0.01) and asthma (30%vs.21%, p<0.05). CONCLUSION: Longitudinal data could be used to study the evolution of multimorbidity and could provide information on CDs mean age of occurrence, order of appearance and impact on the development of future CDs.
Keywords: Humans; Chronic Disease; Morbidity; Prevalence; Longitudinal Studies; Adolescent; Adult; Aged; Middle Aged; South Australia
Rights: © 2014 Ruel et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
RMID: 0030010886
DOI: 10.1371/journal.pone.0096291
Appears in Collections:Medicine publications

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