Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: Association of upper and lower gastrointestinal tract symptoms with body mass index in an Australian cohort
Author: Talley, N.
Quan, C.
Jones, M.
Horowitz, M.
Citation: Neurogastroenterology and Motility, 2004; 16(4):413-419
Publisher: Blackwell Publishing Ltd
Issue Date: 2004
ISSN: 1350-1925
Statement of
N. J. Talley, C. Quan, M. P. Jones & M. Horowitz
Abstract: Food modulates gastrointestinal (GI) function and GI symptoms could alter food intake, but it is not established whether or not obese people experience more or less GI symptoms. We aimed at evaluating the association between body mass index (BMI) and specific GI symptoms in the community. Population-based random samples from Sydney, Australia (n = 777) completed a validated questionnaire. The association of each GI symptom with BMI (kg m2) categories was assessed using logistic regression analysis adjusting for potential confounders. The prevalence of obesity (BMI ≥30 kg m2) was 22%. There were univariate associations (adjusting for age, sex, education level, alcohol and smoking) between increased BMI category and heartburn (OR = 1.9, 95% CI 1.4, 2.5), acid regurgitation (OR = 2.1, 95% CI 1.4, 2.9), increased bloating (OR = 1.3, 95%CI 1.1, 1.6), increased stool frequency (OR = 1.4, 95% CI 1.1, 1.7), loose and watery stools (OR = 1.5, 95% CI 1.1, 2.0) and upper abdominal pain (OR = 1.3, 95% CI 1.03, 1.6). Early satiety was associated with a lower BMI category but this was not significant after adjustment (OR = 0.8, 95% CI 0.6, 1.1). Lower abdominal pain, postprandial fullness, nausea and vomiting were not associated with BMI category. In a regression model adjusting for sex, education, smoking, alcohol and all GI symptoms, older age, less early satiety and increased stool frequency and heartburn were all independently associated with increasing BMI (all P < 0.01). Heartburn and diarrhoea were associated with increased BMI, while early satiety was associated with a lower BMI in this population.
Keywords: body mass index
early satiety
gastro-oesophageal reflux
Description: Article first published online: 22 JUL 2004
Rights: © 2004 Blackwell Publishing Ltd
DOI: 10.1111/j.1365-2982.2004.00530.x
Published version:
Appears in Collections:Aurora harvest
Medicine publications

Files in This Item:
There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.