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Type: Journal article
Title: Gastric emptying in the elderly
Author: Soenen, S.
Rayner, C.
Horowitz, M.
Jones, K.
Citation: Clinics in Geriatric Medicine, 2015; 31(3):339-353
Publisher: Elsevier
Issue Date: 2015
ISSN: 0749-0690
Statement of
Stijn Soenen, Chris K. Rayner, Michael Horowitz, Karen L. Jones
Abstract: Aging is characterized by a diminished homeostatic regulation of physiologic functions, including slowing of gastric emptying. Gastric and small intestinal motor and humoral mechanisms in humans are complex and highly variable: ingested food is stored, mixed with digestive enzymes, ground into small particles, and delivered as a liquefied form into the duodenum at a rate allowing efficient digestion and absorption. In healthy aging, motor function is well preserved whereas deficits in sensory function are more apparent. The effects of aging on gastric emptying are relevant to the absorption of oral medications and the regulation of appetite, postprandial glycemia, and blood pressure.
Keywords: Blood pressure
Breath tests
Gastric emptying
Migrating motor complex
Neural and humoral feedback
Rights: © 2015 Elsevier Inc. All rights reserved.
DOI: 10.1016/j.cger.2015.04.003
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