Please use this identifier to cite or link to this item:
Scopus Web of Science® Altmetric
Type: Journal article
Title: Essential pre-pregnancy and pregnancy interventions for improved maternal, newborn and child health
Author: Lassi, Z.
Mansoor, T.
Salam, R.
Das, J.
Bhutta, Z.
Citation: Reproductive Health, 2014; 11(Suppl. 1):S2-1-S2-19
Publisher: BioMed Central
Issue Date: 2014
ISSN: 1742-4755
Statement of
Zohra S Lassi, Tarab Mansoor, Rehana A Salam, Jai K Das and Zulfiqar A Bhutta
Abstract: The statistics related to pregnancy and its outcomes are staggering: annually, an estimated 250000-280000 women die during childbirth. Unfortunately, a large number of women receive little or no care during or before pregnancy. At a period of critical vulnerability, interventions can be effectively delivered to improve the health of women and their newborns and also to make their pregnancy safe. This paper reviews the interventions that are most effective during preconception and pregnancy period and synergistically improve maternal and neonatal outcomes. Among pre-pregnancy interventions, family planning and advocating pregnancies at appropriate intervals; prevention and management of sexually transmitted infections including HIV; and peri-conceptual folic-acid supplementation have shown significant impact on reducing maternal and neonatal morbidity and mortality. During pregnancy, interventions including antenatal care visit model; iron and folic acid supplementation; tetanus Immunisation; prevention and management of malaria; prevention and management of HIV and PMTCT; calcium for hypertension; anti-Platelet agents (low dose aspirin) for prevention of Pre-eclampsia; anti-hypertensives for treating severe hypertension; management of pregnancy-induced hypertension/eclampsia; external cephalic version for breech presentation at term (>36 weeks); management of preterm, premature rupture of membranes; management of unintended pregnancy; and home visits for women and children across the continuum of care have shown maximum impact on reducing the burden of maternal and newborn morbidity and mortality. All of the interventions summarized in this paper have the potential to improve maternal mortality rates and also contribute to better health care practices during preconception and periconception period.
Keywords: preconception; prepregnancy; pregnancy; essential interventions
Description: This article has been published as part of Reproductive Health Volume 11 Supplement 1, 2014: Essential intervention for maternal, newborn and child health.
Rights: © 2014 Lassi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.
RMID: 0030038046
DOI: 10.1186/1742-4755-11-S1-S2
Appears in Collections:Medicine publications

Files in This Item:
File Description SizeFormat 
hdl_97682.pdfPublished version489.25 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.