Please use this identifier to cite or link to this item: https://hdl.handle.net/2440/9789
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Type: Journal article
Title: Association of aortic stenosis with platelet hyperaggregability and impaired responsiveness to nitric oxide
Author: Chirkov, Y.
Holmes, A.
Willoughby, S.
Stewart, S.
Horowitz, J.
Citation: American Journal of Cardiology, 2002; 90(5):551-554
Publisher: Excerpta Medica Inc
Issue Date: 2002
ISSN: 0002-9149
1879-1913
Statement of
Responsibility: 
Yuliy Y. Chirkov, Andrew S. Holmes, Scott R. Willoughby, Simon Stewart, and John D. Horowitz
Abstract: In summary, the present study demonstrates that AS, irrespective of the presence and/or absence of CAD, is associated with platelet hyperaggregability and hyporesponsiveness to antiaggregatory effects of NO donor SNP. Treatment with the prophylactic antianginal agent perhexiline improves platelet responsiveness to NO.
Keywords: Humans
Aortic Valve Stenosis
Nitroprusside
Nitric Oxide
Aspirin
Perhexiline
Adenosine Diphosphate
Cardiovascular Agents
Platelet Aggregation Inhibitors
Stroke Volume
Severity of Illness Index
Follow-Up Studies
Platelet Aggregation
Ventricular Function, Left
Adult
Aged
Aged, 80 and over
Middle Aged
Female
Male
Coronary Artery Disease
Statistics as Topic
Description: Copyright © 2002 Excerpta Medica Inc. All rights reserved.
DOI: 10.1016/S0002-9149(02)02536-5
Appears in Collections:Aurora harvest 4
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