Effects of quantitative trait loci and the myostatin locus on trace and macro elements (minerals) in bovine liver, muscle and kidney

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dc.contributor.authorMorris, C.
dc.contributor.authorBottema, C.
dc.contributor.authorCullen, N.
dc.contributor.authorHickey, S.
dc.contributor.authorKnowles, S.
dc.contributor.authorPitchford, W.
dc.date.issued2013
dc.description.abstractA quantitative trait locus (QTL) study of the concentrations of 14 trace and macro elements (minerals) in tissues of beef cattle was conducted in New Zealand. Back-cross calves with Jersey and Limousin ancestry (202 heifers and 211 steers) were generated using first-cross sires. This paper reports on testing for effects of QTL on the concentrations of minerals in liver, kidney and muscle in cattle at slaughter, following a growth phase during which rearing and finishing stages were on pasture. Fifteen QTL were identified (P < 0.05) on a genome-wide basis in combined-sire and within-sire analyses. In addition, the possible effect of the Limousin myostatin F94L allele was tested by fitting each calf’s myostatin genotype, and 16 QTL were identified. Twelve were in common with those QTL identified previously, comprising six affecting the liver (copper and zinc, on two chromosomes each; plus iron and molybdenum), three affecting the kidney (calcium, copper and iron), and three affecting muscle (iron, strontium and zinc).
dc.description.statementofresponsibilityC.A. Morris, C.D.K. Bottema, N.G. Cullen, S.M. Hickey, S.O. Knowles and W.S. Pitchford
dc.identifier.citationAnimal Genetics, 2013; 44(4):361-368
dc.identifier.doi10.1111/age.12012
dc.identifier.issn0268-9146
dc.identifier.issn1365-2052
dc.identifier.orcidBottema, C. [0000-0001-6245-0099]
dc.identifier.orcidPitchford, W. [0000-0002-5213-3978]
dc.identifier.urihttp://hdl.handle.net/2440/79249
dc.language.isoen
dc.publisherBlackwell Publishing Ltd
dc.rights© 2012 The Authors, Animal Genetics © 2012 Stichting International Foundation for Animal Genetics
dc.source.urihttps://doi.org/10.1111/age.12012
dc.subjectCattle
dc.subjectelement
dc.subjectJersey
dc.subjectLimousin
dc.subjectmineral
dc.subjectquantitative trait locus (QTL)
dc.titleEffects of quantitative trait loci and the myostatin locus on trace and macro elements (minerals) in bovine liver, muscle and kidney
dc.typeJournal article
pubs.publication-statusPublished

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