A xylazine infusion regimen to provide analgesia in sheep

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dc.contributor.authorGrant, C.
dc.contributor.authorSummersides, G.
dc.contributor.authorKuchel, T.
dc.date.issued2001
dc.description.abstractThe efficacy of continuous low-dose xylazine infusion following an initial loading dose in providing analgesia in sheep was examined using an algesimetry method based on a leg lifting response to an electrical stimulus. Sheep received a 5 mg intramuscular injection of xylazine followed by continuous infusion of intravenous xylazine (2 mg/h) for 90 min. This treatment resulted in significant increases in the level of current required to elicit a leg lifting response (287% of baseline) and steady state analgesia was maintained from 10 min after the start of the infusion until the end of the experimental period. This protocol appears to be a simple and effective regimen for providing steady state analgesia in sheep.
dc.identifier.citationLaboratory Animals, 2001; 35(3):277-281
dc.identifier.doi10.1258/0023677011911606
dc.identifier.issn0023-6772
dc.identifier.issn1758-1117
dc.identifier.urihttp://hdl.handle.net/2440/14751
dc.language.isoen
dc.publisherRoyal Soc Medicine Press Ltd
dc.source.urihttps://doi.org/10.1258/0023677011911606
dc.subjectAnimals
dc.subjectSheep
dc.subjectXylazine
dc.subjectAdrenergic alpha-Agonists
dc.subjectAnalgesia
dc.subjectInjections, Intramuscular
dc.subjectMale
dc.titleA xylazine infusion regimen to provide analgesia in sheep
dc.typeJournal article
pubs.publication-statusPublished

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