Atypical presentations of screen-detected DCIS Implications for pre-operative assessment and surgical intervention
| dc.contributor.author | Farshid, G. | |
| dc.contributor.author | Downey, P. | |
| dc.contributor.author | Gill, P. | |
| dc.date.issued | 2007 | |
| dc.description | Crown copyright © 2006 Published by Elsevier Ltd. | |
| dc.description.abstract | Few series are published on DCIS that forms parenchymal lesions on screening mammograms. The implications of these unusual presentations for pre-operative assessment and surgical intervention are of interest. In the setting of a large, population-based breast cancer screening program, the diagnostic and management implications of DCIS presenting as parenchymal lesions on screening mammograms are investigated. A total of 125 lesions (20.1% of all DCIS) presented as a mass (n=99) or microcalcifications with an associated parenchymal lesion (n=26). Cytology was positive in 47.1% of cases. Core biopsy diagnosed DCIS in 68.4% of cases. Breast surgery after a definite preoperative diagnosis achieved negative initial margins in 69.4% case, versus 54.7% without a pre-operative malignant diagnosis. The mastectomy rate was 26.4%. Axillary surgery was carried out in 32.8% cases, including axillary clearance in 26.4% of cases. One in five cases of DCIS detected during mammographic screening has features other than pure microcalcifications. This has implications for pre-operative assessment and surgical management. | |
| dc.description.statementofresponsibility | Gelareh Farshid, Peter Downey and P.Grantley Gill | |
| dc.description.uri | http://www.elsevier.com/wps/find/journaldescription.cws_home/623010/description#description | |
| dc.identifier.citation | Breast, 2007; 16(2):161-171 | |
| dc.identifier.doi | 10.1016/j.breast.2006.08.003 | |
| dc.identifier.issn | 0960-9776 | |
| dc.identifier.issn | 1532-3080 | |
| dc.identifier.orcid | Farshid, G. [0000-0002-2056-0561] | |
| dc.identifier.orcid | Gill, P. [0000-0001-7310-2970] | |
| dc.identifier.uri | http://hdl.handle.net/2440/42068 | |
| dc.language.iso | en | |
| dc.publisher | Churchill Livingstone | |
| dc.source.uri | https://doi.org/10.1016/j.breast.2006.08.003 | |
| dc.subject | Carcinoma | |
| dc.subject | Cytology | |
| dc.subject | Mammography | |
| dc.subject | Core biopsy | |
| dc.subject | DCIS | |
| dc.subject | Breast cancer screening | |
| dc.title | Atypical presentations of screen-detected DCIS Implications for pre-operative assessment and surgical intervention | |
| dc.type | Journal article | |
| pubs.publication-status | Published |