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Cytokine receptor expression by solid tumours

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dc.contributor.authorRidings, J.
dc.contributor.authorMacardle, P.
dc.contributor.authorByard, R.
dc.contributor.authorSkinner, J.
dc.contributor.authorZola, H.
dc.date.issued1995
dc.description.abstractThe expression of cytokine receptors by a variety of solid tumour tissues was examined, using an immunofluorescence procedure optimized for sensitivity. Several cytokines generally considered as relevant only to the immune and haematopoietic systems were shown to be expressed by solid tumours. For example, breast carcinoma frequently expressed both chains of the IL-3 receptor, the beta chain of the IL-2 receptor, the TNF type two receptor, the signal-transducing chain CD130, and c-kit. The broad expression of cytokine receptors suggests that the receptor profile of individual tumours should be determined before the application of therapy that involves the administration of cytokines.
dc.description.urihttp://www.ncbi.nlm.nih.gov/pubmed/8729878
dc.identifier.citationTherapeutic immunology, 1995; 2(2):67-76
dc.identifier.issn0967-0149
dc.identifier.orcidByard, R. [0000-0002-0524-5942]
dc.identifier.urihttp://hdl.handle.net/2440/7874
dc.language.isoen
dc.subjectHumans
dc.subjectNeoplasms
dc.subjectLymphoma, Non-Hodgkin
dc.subjectNeuroblastoma
dc.subjectMelanoma
dc.subjectBreast Neoplasms
dc.subjectProstatic Neoplasms
dc.subjectReceptors, Cytokine
dc.subjectReceptors, Colony-Stimulating Factor
dc.subjectReceptors, Interleukin
dc.subjectReceptors, Tumor Necrosis Factor
dc.subjectMicroscopy, Fluorescence
dc.subjectFluoroimmunoassay
dc.subjectSensitivity and Specificity
dc.subjectFemale
dc.subjectMale
dc.subjectWilms Tumor
dc.titleCytokine receptor expression by solid tumours
dc.typeJournal article
pubs.publication-statusPublished

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