Brain fog in postural tachycardia syndrome: An objective cerebral blood flow and neurocognitive analysis

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dc.contributor.authorWells, R.
dc.contributor.authorPaterson, F.
dc.contributor.authorBacchi, S.
dc.contributor.authorPage, A.
dc.contributor.authorBaumert, M.
dc.contributor.authorLau, D.H.
dc.date.issued2020
dc.descriptionFirst published: 03 March 2020
dc.description.abstractBackground: It remains unclear whether brain fog is related to impaired cerebral blood flow (CBF) in postural tachycardia syndrome (POTS) patients. Methods: We assessed CBF in the posterior cerebral artery (PCA) using transcranial Doppler with visual stimuli in 11 POTS and 8 healthy subjects in the seated position, followed by neurocognitive testing. Results: CBF parameters were similar between the two groups. POTS patients demonstrated significantly longer latency in delayed match to sample response time and greater errors in attention switching task. Conclusions: Impaired short-term memory and alertness may underlie the symptom of brain fog in POTS patients, despite normal CBF.
dc.description.statementofresponsibilityRachel Wells, Felix Paterson, Stephen Bacchi, Amanda Page, Mathias Baumert, Dennis H. Lau
dc.identifier.citationJournal of Arrhythmia, 2020; 36(3):549-552
dc.identifier.doi10.1002/joa3.12325
dc.identifier.issn1880-4276
dc.identifier.issn1883-2148
dc.identifier.orcidWells, R. [0000-0002-6847-0143]
dc.identifier.orcidBacchi, S. [0000-0001-5130-8628]
dc.identifier.orcidPage, A. [0000-0002-7086-5865]
dc.identifier.orcidBaumert, M. [0000-0003-2984-2167]
dc.identifier.orcidLau, D.H. [0000-0001-7753-1318]
dc.identifier.urihttps://hdl.handle.net/2440/140179
dc.language.isoen
dc.publisherWiley
dc.relation.grantNHMRC
dc.rights© 2020 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
dc.source.urihttps://doi.org/10.1002/joa3.12325
dc.subjectcerebral blood flow velocity; cognitive dysfunction; neurovascular coupling; postural tachycardia syndrome; transcranial Doppler
dc.titleBrain fog in postural tachycardia syndrome: An objective cerebral blood flow and neurocognitive analysis
dc.typeJournal article
pubs.publication-statusPublished

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