Rectal analgesia for the relief of perineal pain after childbirth: a randomised controlled trial of diclofenac suppositories

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dc.contributor.authorDodd, J.
dc.contributor.authorHedayati, H.
dc.contributor.authorPearce, E.
dc.contributor.authorHotham, N.
dc.contributor.authorCrowther, C.
dc.date.issued2004
dc.descriptionThe definitive version is available at www.blackwell-synergy.com
dc.description.abstractObjective: To evaluate rectal diclofenac in the relief of perineal pain after trauma during childbirth. Design: A randomised, double-blind trial. Setting: Delivery Suite, Women's and Children's Hospital, South Australia. Population: Women with a second-degree (or greater) perineal tear or episiotomy. Methods: Women were randomly allocated to either diclofenac or placebo suppositories (Anusol), using a computer-generated randomisation schedule with stratification for parity and mode of birth. Treatment packs contained two × 100 mg diclofenac or two placebo suppositories, the first being inserted when suturing was complete, and the second 12–24 hours after birth. Women were asked to complete questionnaires at 24 and 48 hours after birth relating to their degree of perineal pain using the validated Short Form McGill Pain Questionnaire. Main outcome measures: Pain scores at 24 and 48 hours after birth. Results: A total of 133 women were recruited, with 67 randomised to diclofenac suppositories and 66 to placebo. Women in the diclofenac group were significantly less likely to experience pain at 24 hours while walking (RR 0.8; 95% CI 0.6 to 1.0), sitting (RR 0.8; 95% CI 0.6 to 1.0), passing urine (RR 0.6; 95% CI 0.4 to 1.0) and on opening their bowels (RR 0.6; 95% CI 0.2 to 0.9) compared with those women who received placebo. These differences were not sustained 48 hours after birth. Conclusions: The use of rectal non-steroidal anti-inflammatory drug suppositories is a simple, effective and safe method of reducing the pain experienced by women following perineal trauma within the first 24 hours after childbirth.
dc.description.statementofresponsibilityJodie M. Dodd, Hedyeh Hedayati, Elizabeth Pearce, Neil Hotham, Caroline A. Crowther
dc.identifier.citationBJOG: An International Journal of Obstetrics and Gynaecology, 2004; 111(10):1059-1064
dc.identifier.doi10.1111/j.1471-0528.2004.00156.x
dc.identifier.issn1470-0328
dc.identifier.issn1471-0528
dc.identifier.orcidDodd, J. [0000-0002-6363-4874]
dc.identifier.orcidCrowther, C. [0000-0002-9079-4451]
dc.identifier.urihttp://hdl.handle.net/2440/8062
dc.language.isoen
dc.publisherBlackwell Publishing Ltd
dc.source.urihttp://www.blackwell-synergy.com/doi/abs/10.1111/j.1471-0528.2004.00156.x
dc.subjectPerineum
dc.subjectHumans
dc.subjectPain
dc.subjectPuerperal Disorders
dc.subjectDiclofenac
dc.subjectAnalgesics
dc.subjectAnti-Inflammatory Agents, Non-Steroidal
dc.subjectSuppositories
dc.subjectAdministration, Rectal
dc.subjectDouble-Blind Method
dc.subjectPregnancy
dc.subjectAdult
dc.subjectFemale
dc.titleRectal analgesia for the relief of perineal pain after childbirth: a randomised controlled trial of diclofenac suppositories
dc.typeJournal article
pubs.publication-statusPublished

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