Animal models of traumatic brain injury: a review

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dc.contributor.authorFinnie, J.
dc.date.issued2001
dc.description.abstract<h4>Objective</h4>To review the main types of animal models of traumatic brain injury (TBI), their desirable characteristics and limitations, the major structural changes in the brain modelled, and special features of paediatric TBI modelling.<h4>Conclusion</h4>Animal models have contributed substantially to our understanding of the mechanisms of TBI in humans, but many aspects of closed head injury remain to be elucidated and effective neuroprotective agents are few. Many of the advances in the pathogenesis of human TBI also have application in veterinary medicine and there is ample opportunity for veterinarians to contribute to the selection, development and characterisation of potential animal models of neurotrauma and other disorders and ensure that animal welfare standards are maintained.
dc.identifier.citationAustralian Veterinary Journal, 2001; 79(9):628-633
dc.identifier.doi10.1111/j.1751-0813.2001.tb10785.x
dc.identifier.issn0005-0423
dc.identifier.issn1751-0813
dc.identifier.orcidFinnie, J. [0000-0003-2277-1693]
dc.identifier.urihttp://hdl.handle.net/2440/5537
dc.language.isoen
dc.publisherAustralian Veterinary Assn
dc.source.urihttps://doi.org/10.1111/j.1751-0813.2001.tb10785.x
dc.subjectAnimals
dc.subjectSheep
dc.subjectHumans
dc.subjectBrain Injuries
dc.subjectDisease Models, Animal
dc.subjectSpecies Specificity
dc.subjectCerebrovascular Circulation
dc.subjectAnimal Welfare
dc.subjectAdult
dc.subjectChild
dc.subjectBiomechanical Phenomena
dc.titleAnimal models of traumatic brain injury: a review
dc.typeJournal article
pubs.publication-statusPublished

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