Cleavage of BiP by Subtilase Cytotoxin

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dc.contributor.assigneeAdelaide Research & Innovation
dc.contributor.authorPaton, A.
dc.contributor.authorPaton, J.
dc.contributor.authorBacker, M.
dc.contributor.authorBacker, J.
dc.contributor.organisationAdelaide Research & Innovation Pty Ltd
dc.date.issued2008
dc.description.abstractCleavage of BIP (Immunoglobulin binding protein) by subtilase toxin and its application to inhibiting growth of or killing of cells. This has application to treatment of cancers and to conformational diseases and in particular to conformational diseases involving BiP that are influenced by cleavage by the subtilase cytotoxin. The invention also relates to subtilase toxin molecules specifically targeting proliferating cells, in particular tumor cells, or cells expressing a vascular endothelial growth factor receptor.
dc.identifier.orcidPaton, J. [0000-0001-9807-5278]
dc.identifier.patentInt App No: PCT/AU2007/001111
dc.identifier.urihttp://hdl.handle.net/2440/41856
dc.language.isoen
dc.source.urihttp://www.wipo.int/pctdb/en/wo.jsp?ELEMENT_SET=F&LANGUAGE=ENG&KEY=08/014574&IA=08/014574&DISPLAY=STATUS
dc.titleCleavage of BiP by Subtilase Cytotoxin
dc.typePatent
pubs.publication-statusPublished

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