Review of the ophthalmic manifestations of gout and uric acid crystal deposition

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dc.contributor.authorAo, J.
dc.contributor.authorGoldblatt, F.
dc.contributor.authorCasson, R.J.
dc.date.issued2017
dc.description.abstractGout is a clinical disorder that is characterized by the deposition of monosodium urate crystals (MSU) in joints and tendons, usually in the presence of prolonged hyperuricaemia. Following an asymptomatic phase of hyperuricaemia, gout usually presents as acute monoarthritis followed by periods of remission and exacerbation. Conjunctival hyperaemia and subconjunctival haemorrhage exacerbated by purine intake are two of the more common manifestations that may go unrecognized. Other ocular and adnexal structures can be affected by urate crystal deposition and associated inflammation, with potentially vision-threatening consequences; however, ocular manifestations of gout are rare and may have been over-reported in the older literature, but our understanding of the clinic-pathological features of ocular urate deposits remains limited.
dc.description.statementofresponsibilityJack Ao, Fiona Goldblatt and Robert J Casson
dc.identifier.citationClinical and Experimental Ophthalmology, 2017; 45(1):73-80
dc.identifier.doi10.1111/ceo.12749
dc.identifier.issn1442-6404
dc.identifier.issn1442-9071
dc.identifier.orcidAo, J. [0000-0002-8546-8598]
dc.identifier.orcidCasson, R.J. [0000-0003-2822-4076]
dc.identifier.urihttps://hdl.handle.net/2440/135957
dc.language.isoen
dc.publisherWiley
dc.rights© 2016 Royal Australian and New Zealand College of Ophthalmologists
dc.source.urihttps://doi.org/10.1111/ceo.12749
dc.subjecteyes
dc.subjectgout
dc.subjectmanifestations
dc.subjectocular
dc.subjectophthalmic
dc.titleReview of the ophthalmic manifestations of gout and uric acid crystal deposition
dc.typeJournal article
pubs.publication-statusPublished

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