Influence of nanomaterials on pathogens and mammalian cells /

Date

2018

Authors

Roy Chowdhury, Neelika,

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thesis

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Abstract

Medical device associated infections caused by bacteria is a serious threat to human health and a multibillion dollar burden to healthcare systems across the world. Globally, infection is a leading cause of death. Although an array of treatment approaches such as combination antibiotic therapies are available to deal with these infections, the severity of the problem has not been significantly reduced due to bacterial drug resistance. Therefore, there is a great potential to establish new remedies that can alleviate the problem of antibiotic resistant infections. Noble metals such as gold and silver, and their nanoparticulate forms have been used for centuries as alternative strategies to treat numerous health issues.This thesis focused on the synthesis of aqueous suspensions of “green” silver and gold nanoparticles as well as preparation of plasma coated model substrates with mercaptosuccinic acid modified silver and gold nanoparticles for two specific applications - I) inhibiting bacterial growth and, II) preventing cytotoxicity towards mammalian cells.

School/Discipline

University of South Australia. School of Engineering.
School of Engineering.

Dissertation Note

Thesis (PhD(Mechanical and Manuf Eng))--University of South Australia, 2018.

Provenance

Copyright 2018 Neelika Roy Chowdhury.

Description

1 ethesis (202 pages) :
colour illustrations.
Includes bibliographical references.

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506 0#$fstar $2Unrestricted online access

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