Effects of Precursor and Deposition Conditions on Prevention of Bacterial Biofilm Growth on Chlorinated Plasma Polymers
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(Published version)
Date
2016
Authors
Michl, T.
Coad, B.
Hüsler, A.
Valentin, J.
Vasilev, K.
Griesser, H.
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Journal article
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Plasma Processes and Polymers, 2016; 13(6):654-662
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Abstract
In this work, we aimed to understand the key properties that confer antibacterial activity to chlorinated plasma polymers, by investigating plasma polymers deposited from a series of chlorinated precursor molecules and also investigating the effect of plasma conditions. Results revealed that only precursors with a Cl/C ratio ≥1.5 generate effective antibacterial coatings, whereas the coating thickness is irrelevant. Furthermore there is a “sweet spot” in process conditions to generate coatings with optimal antimicrobial activity. Lastly, we investigated the release of chlorinated fragments and attenuation of the surface-active antibacterial properties of the chlorinated plasma polymers by overcoating them with a perfluorinated plasma polymer
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Copyright 2015 Wiley-VCH Verlag GmbH & Co.
Access Condition Notes: Postprint available after 1 July 2017