Control of fed-batch fermentations
Date
1999
Authors
Lee, J.
Lee, S.
Park, S.
Middelberg, A.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Biotechnology Advances, 1999; 17(1):29-48
Statement of Responsibility
Conference Name
Abstract
Fed-batch fermentation is used to prevent or reduce substrate-associated growth inhibition by controlling nutrient supply. Here we review the advances in control of fed-batch fermentations. Simple exponential feeding and inferential methods are examined, as are newer methods based on fuzzy control and neural networks. Considerable interest has developed in these more advanced methods that hold promise for optimizing fed-batch techniques for complex fermentation systems.