DelIrium VULnerability in GEriatrics (DIVULGE) study: A protocol for a prospective observational study of electroencephalogram associations with incident postoperative delirium

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Date

2021

Authors

Boord, M.S.
Davis, D.H.J.
Psaltis, P.J.
Coussens, S.W.
Feuerriegel, D.
Garrido, M.I.
Bourke, A.
Keage, H.A.D.

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BMJ Neurology Open, 2021; 3(2):e000199-1-e000199-8

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Monique S Boord, Daniel H J Davis, Peter J Psaltis, Scott W Coussens, Daniel Feuerriegel, Marta I Garrido, Alice Bourke, Hannah A D Keage

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Abstract

Delirium is a neurocognitive disorder common in older adults in acute care settings. Those who develop delirium are at an increased risk of dementia, cognitive decline and death. Electroencephalography (EEG) during delirium in older adults is characterised by slowing and reduced functional connectivity, but markers of vulnerability are poorly described. We aim to identify EEG spectral power and event-related potential (ERP) markers of incident delirium in older adults to understand neural mechanisms of delirium vulnerability. Characterising delirium vulnerability will provide substantial theoretical advances and outcomes have the potential to be translated into delirium risk assessment tools.

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

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