Prevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study

Simple item page
dc.contributor.authorRudkin, A.
dc.contributor.authorEdussuriya, K.
dc.contributor.authorSennanayake, S.
dc.contributor.authorSenaratne, T.
dc.contributor.authorSelva-Nayagam, D.
dc.contributor.authorSullivan, T.
dc.contributor.authorCasson, R.
dc.date.issued2008
dc.description.abstractAims: To report the prevalence and correlates of exfoliation syndrome (XFS) in central, rural Sri Lanka. Methods: A population-based, cross-sectional ophthalmic survey of inhabitants 40 years of age and over from villages in the Kandy District was conducted. Selection was randomised using a cluster sampling process. 1721 eligible participants were identified, 1375 participated. A detailed ophthalmic history and examination including ocular biometry was made of each participant. Results: The prevalence of XFS was estimated to be 1.1% (95% CI 0.5 to 1.5%; 22 eyes). XFS was bilateral in eight subjects, unilateral in six subjects. Univariate analysis demonstrated a significant association between XFS and increasing age (p<0.001), increasing intraocular pressure (odds ratio 1.2; 95% CI 1.09 to 1.27; p<0.001), nuclear cataracts (odds ratio 1.92; 95% CI 1.47 to 2.51; p<0.001), visual impairment (odds ratio 9.72; 95% CI 3.01 to 31.44; p<0.001) and a history of hypertension (odds ratio 3.89; 95% CI 1.14 to 13.16; p = 0.030). Conclusion: XFS in this Sri Lankan population was associated with advanced age, raised intraocular pressure, nuclear cataracts, hypertension and visual impairment.
dc.description.statementofresponsibilityA. K. Rudkin, K. Edussuriya, S. Sennanayake, T. Senaratne, D. Selva, T. R. Sullivan, R. J. Casson
dc.identifier.citationBritish Journal of Ophthalmology, 2008; 92(12):1595-1598
dc.identifier.doi10.1136/bjo.2008.146407
dc.identifier.issn0007-1161
dc.identifier.issn1468-2079
dc.identifier.orcidRudkin, A. [0000-0003-2508-8574]
dc.identifier.orcidSelva-Nayagam, D. [0000-0002-2169-5417]
dc.identifier.orcidSullivan, T. [0000-0002-6930-5406]
dc.identifier.orcidCasson, R. [0000-0003-2822-4076]
dc.identifier.urihttp://hdl.handle.net/2440/52357
dc.language.isoen
dc.publisherBritish Med Journal Publ Group
dc.source.urihttps://doi.org/10.1136/bjo.2008.146407
dc.subjectHumans
dc.subjectOptic Nerve Diseases
dc.subjectGlaucoma
dc.subjectExfoliation Syndrome
dc.subjectDisease Progression
dc.subjectPrevalence
dc.subjectCross-Sectional Studies
dc.subjectAge Factors
dc.subjectBiometry
dc.subjectIntraocular Pressure
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectRural Health
dc.subjectSri Lanka
dc.subjectFemale
dc.subjectMale
dc.titlePrevalence of exfoliation syndrome in central Sri Lanka: the Kandy Eye Study
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Opthalmology & Visual Sciences publications