Regulation and mechanism of autophagy-dependent developmental cell death in Drosophila Melanogaster larval midgut /
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(Published version)
Date
2016
Authors
Xu, Tianqi,
Editors
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Type:
thesis
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Abstract
Programmed cell death (PCD) is defined as cell death mediated by an intracellular program and carried out in a regulated manner. It is of great importance to multicellular organisms, both during development and at adult stage. The presence of autophagy markers in dying cells is well documented and there is growing evidence for a role of autophagy as an independent PCD mechanism. In particular, the removal of the Drosophila larval midgut during metamorphosis depends on autophagy rather than apoptosis, the more common form of PCD. As a recently discovered mode of PCD, the mechanisms by which autophagy mediates cell death remain poorly defined. The focus of this study is to understand the mechanisms and regulation of autophagy-dependent cell death.
School/Discipline
University of South Australia. Centre for Cancer Biology.
Centre for Cancer Biology.
Centre for Cancer Biology.
Dissertation Note
Thesis (PhD(Medical Science))--University of South Australia, 2016.
Provenance
Copyright 2016 Tianqi Su.
Description
1 ethesis (xiii, 147 pages) :
colour illustrations
Includes bibliographical references (pages 134 -143)
colour illustrations
Includes bibliographical references (pages 134 -143)
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506 0#$fstar $2Unrestricted online access