Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease

Simple item page
dc.contributor.authorAppleton, S.
dc.contributor.authorPoole, P.
dc.contributor.authorSmith, B.
dc.contributor.authorVeale, A.
dc.contributor.authorLasserson, T.
dc.contributor.authorChan, M.
dc.date.issued2006
dc.descriptionArticle No.: CD001104
dc.description.abstractThis review aims to determine the effectiveness of long-acting beta-agonists, salmeterol or formoterol, in the treatment of COPD (emphysema/chronic bronchitis). These drugs improve airflow in the lungs, and enable people with COPD to get on with their daily activities. Twenty-four studies (6061 participants) reported the effects of LABAs in people with COPD. People taking salmeterol 50 mcg daily do have fewer exacerbations than those on placebo, and some improvement in lung function and certain quality of life scores. The findings were not consistent enough to support a general recommendation for the use of these drugs in the group of people with COPD with minimal variation in their lung function, although there is some evidence of improvement in important outcomes and these findings require further exploration in additional trials
dc.description.statementofresponsibilitySarah Appleton; Phillippa Poole; Brian Smith; Antony Veale; Toby J Lasserson; Matthew Ming Ki Chan; Christopher J Cates
dc.identifier.citationCochrane Database of Systematic Reviews, 2006; 3(1):1104-1104
dc.identifier.doi10.1002/14651858.CD001104.pub2
dc.identifier.issn1469-493X
dc.identifier.issn1361-6137
dc.identifier.orcidAppleton, S. [0000-0001-7292-9714]
dc.identifier.urihttp://hdl.handle.net/2440/23419
dc.language.isoen
dc.publisherUpdate Software Ltd
dc.source.urihttps://doi.org/10.1002/14651858.cd001104.pub2
dc.subjectHumans
dc.subjectLung Diseases, Obstructive
dc.subjectEthanolamines
dc.subjectAlbuterol
dc.subjectAdrenergic beta-Agonists
dc.subjectBronchodilator Agents
dc.subjectRandomized Controlled Trials as Topic
dc.subjectFormoterol Fumarate
dc.subjectSalmeterol Xinafoate
dc.titleLong-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Medicine publications