Neonatal outcome of pregnancies complicated by hypertensive disorders between 34 and 37 weeks of gestation: a 7 year retrospective analysis of a national registry

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dc.contributor.authorLangenveld, J.
dc.contributor.authorRavelli, A.
dc.contributor.authorvan Kaam, A.
dc.contributor.authorvan der Ham, D.
dc.contributor.authorvan Pampus, M.
dc.contributor.authorPorath, M.
dc.contributor.authorMol, B.
dc.contributor.authorGanzevoort, W.
dc.date.issued2011
dc.description.abstractObjective: The objective of the study was to determine the neonatal morbidity in late preterm infants born from mothers with a hypertensive disorder. Study Design: Data were obtained from the national Perinatal Registry in The Netherlands on women who delivered between 34+0 and 36+6 weeks with gestational hypertension (n = 4316), preeclampsia (n = 1864), and normotensive controls (n = 20,749). Results: Children from mothers with preeclampsia had an increased risk for admission to the neonatal intensive care unit compared with children from normotensive mothers (odds ratio [OR], 2.0; 95% confidence interval [CI], 1.8–2.2). A cesarean delivery and decreasing gestational age were independent risk factors for neonatal respiratory morbidity. Gestational hypertension or preeclampsia reduced the risk of respiratory distress syndrome compared with the control group (OR, 0.81; 95% CI, 0.64–1.0 and OR, 0.69; 95% CI, 0.49–0.96, respectively). Conclusion: Neonatal morbidity in the late preterm period is considerable. Hypertensive disorders appear to protect for neonatal respiratory morbidity, but higher rates of cesarean section diminish this protective effect.
dc.description.statementofresponsibilityJosje Langenveld, Anita C.J. Ravelli, Anton H. van Kaam, David P. van der Ham, Maria G. van Pampus, Martina Porath, Ben Willem Mol, Wessel Ganzevoort
dc.identifier.citationAmerican Journal of Obstetrics and Gynecology, 2011; 205(6):540.e1-540.e7
dc.identifier.doi10.1016/j.ajog.2011.07.003
dc.identifier.issn0002-9378
dc.identifier.issn1097-6868
dc.identifier.orcidMol, B. [0000-0001-6887-0262] [0000-0001-8337-550X]
dc.identifier.urihttp://hdl.handle.net/2440/85714
dc.language.isoen
dc.publisherMosby
dc.rights© 2011 Mosby, Inc. All rights reserved.
dc.source.urihttps://doi.org/10.1016/j.ajog.2011.07.003
dc.subjectNewborn; preeclampsia; preterm; respiratory distress syndrome
dc.titleNeonatal outcome of pregnancies complicated by hypertensive disorders between 34 and 37 weeks of gestation: a 7 year retrospective analysis of a national registry
dc.typeJournal article
pubs.publication-statusPublished

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