Aggressive inflammatory pseudotumor of the maxillary sinus and orbit

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dc.contributor.authorChong, S.
dc.contributor.authorTeh, C.S.L.
dc.contributor.authorSingh, S.
dc.contributor.authorSeong, M.K.
dc.contributor.authorViswaraja, S.
dc.date.issued2014
dc.description.abstractInflammatory pseudotumor (IPT) is a rare, locally aggressive, benign neoplasm of unknown etiology. It is uncommon in the head and neck region, particularly in the paranasal sinuses. We present an unusual case of IPT of the maxillary sinus and orbit in a 27-year-old woman who presented with cheek swelling, right orbital swelling, double vision, and associated fever and trismus. Computed tomography identified a mass with radiologic features suggestive of a malignancy of the maxillary sinus and orbit; the mass extended into the infratemporal fossa, parapharyngeal space, anterior antral wall, and surrounding soft tissue. A diagnosis of IPT was established on the basis of histologic and immunohistochemical analysis, which identified a proliferation of bland spindle cells and a mixed inflammatory cell infiltrate. Despite its aggressive appearance, IPT is associated with a good prognosis. Our patient was treated successfully with a combination of surgery, steroid therapy, and methotrexate. Chemotherapeutic agents are generally reserved for recalcitrant cases.
dc.description.statementofresponsibilitySheldon Chong, Carren S.L. Teh, Shashinder Singh, Mun Kein Seong, Subrayan Viswaraja
dc.identifier.citationEar, Nose & Throat Journal, 2014; 93(3):108-111
dc.identifier.doi10.1177/014556131409300308
dc.identifier.issn0145-5613
dc.identifier.issn1942-7522
dc.identifier.urihttp://hdl.handle.net/2440/97036
dc.language.isoen
dc.publisherVendome Group LLC
dc.rightsCopyright of ENT: Ear, Nose & Throat Journal is the property of Vendome Group LLC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use.
dc.source.urihttp://www.entjournal.com/article/aggressive-inflammatory-pseudotumor-maxillary-sinus-and-orbit
dc.subjectMaxillary Sinus
dc.subjectParanasal Sinus Diseases
dc.subjectGranuloma, Plasma Cell
dc.subjectAdrenal Cortex Hormones
dc.subjectAntimetabolites, Antineoplastic
dc.titleAggressive inflammatory pseudotumor of the maxillary sinus and orbit
dc.typeJournal article
pubs.publication-statusPublished

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