Quantities of Clostridium botulinum organisms and toxin in feces and presence of Clostridium botulinum toxin in the serum of an infant with botulism

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dc.contributor.authorPaton, J.
dc.contributor.authorLawrence, A.
dc.contributor.authorSteven, I.
dc.date.issued1983
dc.description.abstractA 7-week-old boy presented with symptoms and signs characteristic of infant botulism, and the diagnosis was confirmed by the detection of Clostridium botulinum type A organisms and toxin in the feces. The levels of organisms and toxin in the feces were measured throughout the 81-day period in hospital. The maximum levels detected were 2.46 x 10(8) C. botulinum type A colony-forming units and 64,000 mouse 100% lethal doses of type A toxin per g (wet weight) of feces. C. botulinum toxin was also detected in two samples of the patient's serum, collected 3 and 10 days after admission. Improvement in the patient's clinical condition occurred before the levels of organisms and toxin in the feces reached their maxima. A slight improvement may also have occurred while toxin was still present in the serum.
dc.description.statementofresponsibilityJames C. Paton, Andrew J. Lawrence, and Ian M. Steven
dc.identifier.citationJournal of Clinical Microbiology, 1983; 17(1):13-15
dc.identifier.doi10.1128/jcm.17.1.13-15.1983
dc.identifier.issn0095-1137
dc.identifier.issn1098-660X
dc.identifier.orcidPaton, J. [0000-0001-9807-5278]
dc.identifier.urihttp://hdl.handle.net/2440/85786
dc.language.isoen
dc.publisherAmerican Society for Microbiology
dc.rights© 1983, American Society for Microbiology
dc.source.urihttp://jcm.asm.org/content/17/1/13
dc.subjectFeces
dc.subjectHumans
dc.subjectClostridium botulinum
dc.subjectBotulism
dc.subjectBotulinum Toxins
dc.subjectInfant
dc.subjectMale
dc.titleQuantities of Clostridium botulinum organisms and toxin in feces and presence of Clostridium botulinum toxin in the serum of an infant with botulism
dc.typeJournal article
pubs.publication-statusPublished

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