Variability of MEP amplitude and latency in health and disease
Date
2018
Authors
Uy, J.
Hordacre, B.
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Jaberzadeh, S.
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Book chapter
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Source details - Title: A closer look at motor-evoked potential, 2018 / Jaberzadeh, S. (ed./s), Ch.3, pp.33-51
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Abstract
Motor evoked potentials(MEP) are widely used in the evaluation of the nervous system. MEP values such as amplitude and latency are measured to ascertain the level of corticospinal activity and excitability. Numerous physiological, experiemental and pathological factors can influence MEP measures. A variety of internal factors such as gender, age, arousal and fatigue as well as external factors such as coil positioning, stimulus intensity or stimulus interval can result in the variability of MEP values. This warrants the need for stringent experimental conditions and methodological parameters in it’s use and analysis. This chapter will discuss the use of MEP amplitude and latency in measuring the level of excitability of the corticospinal pathway. It will present the intrinsic and extrinsic factors that influence the variability of these parameters and discuss methods proposed to ensure the clinical usefulness of MEPs as an index of cortical excitability and reorganisation.
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Copyright 2019 Nova Science Publishers