The structures of the frenatin peptides from the skin secretion of the giant tree frog litoria infrenata

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dc.contributor.authorRaferty, M.
dc.contributor.authorWaugh, R.
dc.contributor.authorBowie, J.
dc.contributor.authorWallace, J.
dc.contributor.authorTyler, M.
dc.date.issued1996
dc.description.abstractThe granular dorsal glands of the giant tree frog Litoria infrafrenata contain five peptides including caerulein (a known neuropeptide), and four new peptides named frenatins 1 (MH+ = 1140 Da), 2 (1423), 3 (2180) and 4 (2493). The amino acid sequences of the frenatins are detailed: their structures do not correspond to those of peptides isolated from other amphibians or animals. Frenatin 3, Gly-Leu-Met-Ser-Val-Leu-Gly-His-Ala-Val-Gly-Asn-Val-Leu-Gly- Gly-Leu-Phe-Lys-Pro-Lys-Ser-(OH), has wide spectrum antimicrobial properties.
dc.description.statementofresponsibilityM. J. Raftery, R. J. Waugh, J. H. Bowie, J. C. Wallace and M. J. Tyler
dc.identifier.citationJournal of Peptide Science, 1996; 2(2):117-124
dc.identifier.doi10.1002/psc.60
dc.identifier.issn1075-2617
dc.identifier.issn1099-1387
dc.identifier.urihttp://hdl.handle.net/2440/11343
dc.language.isoen
dc.publisherEuropean Peptide Society : John Wiley & Sons
dc.relation.grantARC
dc.rights© 1996 European Peptide Society and John Wiley & Sons, Ltd.
dc.subjectpeptides
dc.subjectneuropeptide
dc.subjectantimicrobial agent
dc.subjectskin secretion
dc.subjectfrogs
dc.titleThe structures of the frenatin peptides from the skin secretion of the giant tree frog litoria infrenata
dc.typeJournal article
pubs.publication-statusPublished

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