Dietary supplementation with orange juice and carrot juice in cigarette smokers lowers oxidation products in copper oxidised low density lipoproteins

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dc.contributor.authorAbbey, M.
dc.contributor.authorNoakes, M.
dc.contributor.authorNestel, P.
dc.date.issued1995
dc.description.abstract<h4>Objective</h4>Our objective was to evaluate the effect of daily supplementation with foods high in vitamin C and beta carotene on plasma vitamin levels and oxidation of low-density lipoprotein (LDL) in cigarette smokers.<h4>Subjects</h4>Fifteen normolipidemic male cigarette smokers who did not usually take vitamin supplements were recruited into the study.<h4>Interventions</h4>Throughout the study, subjects consumed a diet rich in polyunsaturated fatty acids, which provided 36% of energy as fat: 18% from meat, dairy products, vegetable oils, and fat spreads and 18% from walnuts (68 g/day). Subjects consumed a vitamin-free drink daily for 3 weeks; then for 3 weeks they consumed daily supplements of orange juice (145 mg vitamin C) and carrot juice (16 mg beta carotene).<h4>Results</h4>Vitamin-rich food supplements raised plasma levels of ascorbic acid (1.6-fold; P < .01) and beta carotene (2.6-fold; P < .01). Malondialdehyde, one end product of oxidation, was lower in copper-oxidized LDL after vitamin supplementation (mean +/- standard error = 65.7 +/- 2.0 and 57.5 +/- 2.9 mumol/g LDL protein before and after supplementation, respectively; P < .01). Rate of LDL oxidation and lag time before the onset of LDL oxidation were not affected by antioxidant supplementation.<h4>Conclusions</h4>In habitual cigarette smokers, antioxidant vitamins, which can be feasibly provided from food, partly protected LDL from oxidation despite a diet rich in polyunsaturated fatty acids.
dc.identifier.citationJournal of the American Dietetic Association, 1995; 95(6):671-675
dc.identifier.doi10.1016/S0002-8223(95)00183-2
dc.identifier.issn0002-8223
dc.identifier.issn1878-3570
dc.identifier.urihttp://hdl.handle.net/2440/11960
dc.language.isoen
dc.publisherThe Association
dc.source.urihttps://doi.org/10.1016/s0002-8223(95)00183-2
dc.subjectHumans
dc.subjectDaucus carota
dc.subjectCitrus
dc.subjectCopper
dc.subjectMalondialdehyde
dc.subjectAscorbic Acid
dc.subjectCarotenoids
dc.subjectbeta Carotene
dc.subjectLipids
dc.subjectCholesterol, Dietary
dc.subjectFatty Acids
dc.subjectFatty Acids, Unsaturated
dc.subjectLipoproteins, LDL
dc.subjectDiet
dc.subjectSmoking
dc.subjectOxidation-Reduction
dc.subjectBeverages
dc.subjectFood, Fortified
dc.subjectAdult
dc.subjectMiddle Aged
dc.subjectDiet Records
dc.subjectMale
dc.titleDietary supplementation with orange juice and carrot juice in cigarette smokers lowers oxidation products in copper oxidised low density lipoproteins
dc.typeJournal article
pubs.publication-statusPublished

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