The use of dexmedetomidine as an adjuvant to benzodiazepine-based therapy to decrease the severity of delirium in alcohol withdrawal in adult intensive care unit patients: a systematic review protocol

Date

2014

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Dabrow Woods, A.
Giometti, R.
Weeks, S.

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The JBI Database of Systematic Reviews and Implementation Reports, 2014; 12(1):74-89

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Anne Dabrow Woods, Renee Giometti, Susan Weeks

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Abstract

Review question/objective - In adult intensive care unit patients experiencing alcohol withdrawal, does the use of dexmedetomidine as an adjuvant to benzodiazepine-based therapy decrease delirium severity more effectively than benzodiazepine-based therapy alone? The objective of the systematic review is to examine the best available evidence of the clinical effectiveness of dexmedetomidine as an adjuvant to benzodiazepine-based therapy versus benzodiazepine-based therapy alone, in decreasing delirium severity associated with alcohol withdrawal in adult intensive care unit patients over the age of 18 years.

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