The prevalence, severity, and correlates of psychological distress and impaired health-related quality of life following treatment for testicular cancer: a survivorship study

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dc.contributor.authorSmith, A.B.
dc.contributor.authorButow, P.
dc.contributor.authorOlver, I.
dc.contributor.authorLuckett, T.
dc.contributor.authorGrimison, P.
dc.contributor.authorToner, G.C.
dc.contributor.authorStockler, M.R.
dc.contributor.authorHovey, E.
dc.contributor.authorStubbs, J.
dc.contributor.authorTurner, S.
dc.contributor.authorHruby, G.
dc.contributor.authorGurney, H.
dc.contributor.authorAlam, M.
dc.contributor.authorCox, K.
dc.contributor.authorKing, M.T.
dc.date.issued2016
dc.description.abstractPurpose: This study aimed to establish the prevalence, severity, and correlates of psychological distress and impaired generic health-related quality of life (HRQOL) in testicular cancer (TC) survivors. Methods: Men who had completed active anti-cancer treatment for TC between 6 months and 5 years previously showing no evidence of recurrence were recruited from 14 Australian cancer centers from September 2009 to February 2011. Participants completed a self-report questionnaire measuring demographic, disease, and treatment information, psychological distress (i.e., depression, anxiety, and stress; DASS21), generic health-related quality of life (HRQOL; SF-36v2), TC-specific HRQOL (EORTC QLQ-TC26), coping (MAC), social support (DUFSS), and unmet needs (CaSUN). Results: Of 486 eligible TC survivors, 244 (50.2 %) completed the questionnaire. Compared with normative data, TC survivors reported: small but statistically significant increases in mean levels of anxiety and depression; a greater prevalence of moderate to extremely severe anxiety (19 %) and depression (20 %); and significant deficits to mostly mental aspects of generic HRQOL. The most problematic TC-specific HRQOL issues (e.g., fear of recurrence) were also more mental than physical. In multiple regression analyses, the strongest correlates of psychological distress and impaired generic HRQOL were psychosocial (e.g., helpless/hopeless coping and lower social support) rather than disease or treatment factors. Conclusions: Generally, TC survivors appear to experience mild psychological distress and HRQOL impairments, while a vulnerable subgroup experience more severe morbidity.
dc.description.statementofresponsibilityAllan Ben Smith, Phyllis Butow, Ian Olver, Tim Luckett, Peter Grimison, Guy C. Toner, Martin R Stockler, Elizabeth Hovey, John Stubbs, Sandra Turner, George Hruby, Howard Gurney, Mahmood Alam, Keith Cox, Madeleine T. King
dc.identifier.citationJournal of Cancer Survivorship, 2016; 10(2):223-233
dc.identifier.doi10.1007/s11764-015-0468-5
dc.identifier.issn1932-2259
dc.identifier.issn1932-2267
dc.identifier.orcidOlver, I. [0000-0001-5478-1576]
dc.identifier.urihttp://hdl.handle.net/2440/104169
dc.language.isoen
dc.publisherSpringer
dc.relation.grantNHMRC
dc.rights© Springer Science+Business Media New York 2015
dc.source.urihttps://doi.org/10.1007/s11764-015-0468-5
dc.subjectTesticular cancer; survivorship; psychological distress; health-related quality of life; oncology
dc.titleThe prevalence, severity, and correlates of psychological distress and impaired health-related quality of life following treatment for testicular cancer: a survivorship study
dc.typeJournal article
pubs.publication-statusPublished

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