Current studentsExisting staffContact us
 

Wastewater-based epidemiology to assess pan-European pesticide exposure

Simple item page
dc.contributor.authorRousis, N.I.
dc.contributor.authorGracia Lor, E.
dc.contributor.authorZuccato, E.
dc.contributor.authorBade, R.
dc.contributor.authorBaz Lomba, J.A.
dc.contributor.authorCastrignanò, E.
dc.contributor.authorCausanilles, A.
dc.contributor.authorCovaci, A.
dc.contributor.authorde Voogt, P.
dc.contributor.authorHernàndez, F.
dc.contributor.authorKasprzyk Hordern, B.
dc.contributor.authorKinyua, J.
dc.contributor.authorMcCall, A.K.
dc.contributor.authorPlósz, B.G.
dc.contributor.authorRamin, P.
dc.contributor.authorRyu, Y.
dc.contributor.authorThomas, K.V.
dc.contributor.authorvan Nuijs, A.
dc.contributor.authorYang, Z.
dc.contributor.authorCastiglioni, S.
dc.date.issued2017
dc.descriptionData source: Supplementary data, http://www.sciencedirect.com/science/MiamiMultiMediaURL/1-s2.0-S0043135417304086/1-s2.0-S0043135417304086-mmc1.docx/271768/html/S0043135417304086/7abe5742b886294f0b249e797dd48df6/mmc1.docx
dc.description.abstractHuman biomonitoring, i.e. the determination of chemicals and/or their metabolites in human specimens, is the most common and potent tool for assessing human exposure to pesticides, but it suffers from limitations such as high costs and biases in sampling. Wastewater-based epidemiology (WBE) is an innovative approach based on the chemical analysis of specific human metabolic excretion products (biomarkers) in wastewater, and provides objective and real-time information on xenobiotics directly or indirectly ingested by a population. This study applied the WBE approach for the first time to evaluate human exposure to pesticides in eight cities across Europe. 24 h-composite wastewater samples were collected from the main wastewater treatment plants and analyzed for urinary metabolites of three classes of pesticides, namely triazines, organophosphates and pyrethroids, by liquid chromatography-tandem mass spectrometry. The mass loads (mg/day/1000 inhabitants) were highest for organophosphates and lowest for triazines. Different patterns were observed among the cities and for the various classes of pesticides. Population weighted loads of specific biomarkers indicated higher exposure in Castellon, Milan, Copenhagen and Bristol for pyrethroids, and in Castellon, Bristol and Zurich for organophosphates. The lowest mass loads (mg/day/1000 inhabitants) were found in Utrecht and Oslo. These results were in agreement with several national statistics related to pesticides exposure such as pesticides sales. The daily intake of pyrethroids was estimated in each city and it was found to exceed the acceptable daily intake (ADI) only in one city (Castellon, Spain). This was the first large-scale application of WBE to monitor population exposure to pesticides. The results indicated that WBE can give new information about the “average exposure” of the population to pesticides, and is a useful complementary biomonitoring tool to study population-wide exposure to pesticides.
dc.identifier.citationWater Research, 2017; 121:270-279
dc.identifier.doi10.1016/j.watres.2017.05.044
dc.identifier.issn0043-1354
dc.identifier.issn1879-2448
dc.identifier.urihttps://hdl.handle.net/11541.2/127262
dc.language.isoen
dc.publisherI W A Publishing
dc.relation.fundingEuropean Union 317205 - SEWPROF
dc.relation.fundingGeneralitat Valenciana, Conselleria d'Educacio, Investigacio, Cultura i Esport (APOSTD)
dc.rightsCopyright 2017 Elsevier Access Condition Notes: Postprint available after 1 July 2019
dc.source.urihttps://doi.org/10.1016/j.watres.2017.05.044
dc.subjecturban wastewater
dc.subjectmass spectrometry
dc.subjectpesticides
dc.subjecthuman urinary metabolites
dc.subjectbiomonitoring
dc.subjecthuman intake
dc.titleWastewater-based epidemiology to assess pan-European pesticide exposure
dc.typeJournal article
pubs.publication-statusPublished
ror.fileinfo12146556310001831 13146556300001831 9916138211901831
ror.mmsid9916138211901831

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
9916138211901831.pdf
Size:
427.25 KB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections