O3‐14‐04: A pilot cluster RCT to test the preliminary efficacy of an Alzheimer's family caregiver intervention in Hanoi, Vietnam
Date
2019
Authors
Hinton, L.
Nguyen, H.
Pham, T.
Trong, H.N.
Harvey, D.J.
Thanh, B.N.
Thi Thanh, B.N.
Ngoc, A.N.
Hong, C.N.
Thi Hoai, T.N.
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Journal article
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Alzheimer's and Dementia, 2019; 15(7S):924-924
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Abstract
Background: Vietnam and other low and lower middle income countries are experiencing a dramatic growth in the number of persons with dementia yet very little is known about interventions and programs to support family caregivers in these countries
Methods: Clusters, defined as geographic areas served by commune health stations, were randomly assigned to either the intervention (REACH VN) or an enhanced control condition. To be eligible, caregivers needed to be family members identified as providing the most day-to-day care, age ≥ 18, have a score of ≥ 6 on the 4-item version of the Zarit Burden Inventory (ZBI), and be caring for an older adult previously diagnosed with dementia. Caregivers in clusters randomized to the intervention arm received 4–6 in-home or phone sessions over 2–3 months based on the manualized REACH VN protocol. Caregivers in the enhanced control condition received a single educational session. Primary outcomes included the 4-item ZBI and the 4-item Patient Health Questionnaire (PHQ-4) which were assessed at enrollment and three months later by research assistants masked to allocation.
Results: Of the 10 communes randomized, one was dropped because of low caregiver enrollment. Based on analysis of the 51 caregivers who completed the study, there were no differences in ZBI (p=0.9) or PHQ-4 (p=0.9) between the REACH VN and enhanced control groups at baseline. Using analysis of covariance to evaluate the intervention effect, with the month three assessment as the outcome and the baseline assessment as a covariate, we found that the REACH VN intervention group had an average ZBI score 1.2 SD lower (p=0.02) and a PHQ-4 score 0.7 SD (p=0.03) lower than the enhanced control group.
Conclusions: In the first test of a family caregiver intervention in Vietnam, a relatively brief culturally adapted family caregiver intervention (REACH-VN) was found to have good preliminary efficacy compared with an enhanced control condition.
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Copyright 2019 The Alzheimer's Association