Protein delivery in mechanically ventilated adults in Australia and New Zealand: current practice

Simple item page
dc.contributor.authorArunachala Murthy, T.
dc.contributor.authorBellomo, R.
dc.contributor.authorChapman, M.
dc.contributor.authorDeane, A.
dc.contributor.authorFerrie, S.
dc.contributor.authorFinnis, M.
dc.contributor.authorHurford, S.
dc.contributor.authorO'Connor, S.
dc.contributor.authorPeake, S.
dc.contributor.authorSummers, M.
dc.contributor.authorWilliams, P.
dc.contributor.authorYoung, P.
dc.contributor.authorChapple, L.-A.
dc.date.issued2021
dc.description.abstractObjective: To quantify current protein prescription and delivery in critically ill adults in Australia and New Zealand and compare it with international guidelines. Design: Prospective, multicentre, observational study. Setting: Five intensive care units (ICUs) across Australia and New Zealand. Participants: Mechanically ventilated adults who were anticipated to receive enteral nutrition for ≥ 24 hours. Main outcome measures: Baseline demographic and nutrition data in ICU, including assessment of requirements, prescription and delivery of enteral nutrition, parenteral nutrition and protein supplementation, were collected. The primary outcome was enteral nutrition protein delivery (g/ kg ideal body weight [IBW] per day). Data are reported as mean ± standard deviation or n (%). Results: 120 patients were studied (sex, 60% male; mean age, 59 ± 16 years; mean admission APACHE II score, 20 ± 8). Enteral nutrition was delivered on 88%, parenteral nutrition on 6.8%, and protein supplements on 0.3% of 1156 study days. For the 73% (88/120) of patients who had a nutritional assessment, the mean estimated protein requirements were 99 ± 22 g/day (1.46 ± 0.55 g/kg IBW per day). The mean daily protein delivery was 54 ± 23 g (0.85 ± 0.35 g/kg IBW per day) from enteral nutrition and 56 ± 23 g (0.88 ± 0.35 g/kg IBW per day) from all sources (enteral nutrition, parenteral nutrition, protein supplements). Protein delivery was ≥ 1.2 g/kg IBW per day on 29% of the total study days per patient. Conclusions: Protein delivery as a part of current usual care to critically ill adults in Australia and New Zealand remains below that recommended in international guidelines.
dc.description.statementofresponsibilityTejaswini Arunachala Murthy, Rinaldo Bellomo, Marianne J Chapman, Adam M Deane, Suzie Ferrie, Mark E Finnis, Sally Hurford, Stephanie N O, Connor, Sandra L Peake, Matthew J Summers, Patricia J Williams, Paul J Young, and Lee-anne S Chapple, for the TARGET Protein Management Committee
dc.identifier.citationCritical Care and Resuscitation, 2021; 23(4):386-393
dc.identifier.doi10.51893/2021.4.OA3
dc.identifier.issn1441-2772
dc.identifier.issn2652-9335
dc.identifier.orcidArunachala Murthy, T. [0000-0003-3793-3552]
dc.identifier.orcidChapman, M. [0000-0003-0710-3283]
dc.identifier.orcidDeane, A. [0000-0002-7620-5577]
dc.identifier.orcidFinnis, M. [0000-0003-4125-5221]
dc.identifier.orcidO'Connor, S. [0000-0002-4177-4059]
dc.identifier.orcidPeake, S. [0000-0001-6682-7973]
dc.identifier.orcidWilliams, P. [0000-0002-3948-5573]
dc.identifier.orcidChapple, L.-A. [0000-0002-9818-2484]
dc.identifier.urihttps://hdl.handle.net/2440/134820
dc.language.isoen
dc.publisherCollege Of Intensive Care Medicine Of Australia And New Zealand
dc.relation.granthttp://purl.org/au-research/grants/arc/APP1144496
dc.rightscopyright status unknown
dc.source.urihttps://ccr.cicm.org.au/journal-editions/articles/1456
dc.subjectTARGET Protein Management Committee
dc.titleProtein delivery in mechanically ventilated adults in Australia and New Zealand: current practice
dc.typeJournal article
pubs.publication-statusPublished

Files

Collections

Medicine publications