Novel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancer

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dc.contributor.authorPonnusamy, S.
dc.contributor.authorCoss, C.
dc.contributor.authorThiyagarajan, T.
dc.contributor.authorWatts, K.
dc.contributor.authorHwang, D.-J.
dc.contributor.authorHe, Y.
dc.contributor.authorSelth, L.
dc.contributor.authorMcEwan, I.
dc.contributor.authorDuke, C.
dc.contributor.authorPagadala, J.
dc.contributor.authorSingh, G.
dc.contributor.authorWake, R.
dc.contributor.authorLedbetter, C.
dc.contributor.authorTilley, W.
dc.contributor.authorMoldoveanu, T.
dc.contributor.authorDalton, J.
dc.contributor.authorMiller, D.
dc.contributor.authorNarayanan, R.
dc.date.issued2017
dc.description.abstractAbstract not available
dc.description.statementofresponsibilitySuriyan Ponnusamy, Christopher C. Coss, Thirumagal Thiyagarajan, Kate Watts, Dong-Jin Hwang, Yali He, Luke A. Selth, Iain J. McEwan, Charles B. Duke, Jayaprakash Pagadala, Geetika Singh, Robert W. Wake, Christopher Ledbetter, Wayne D. Tilley, Tudor Moldoveanu, James T. Dalton, Duane D. Miller and Ramesh Narayanan
dc.identifier.citationCancer Research, 2017; 77(22):6282-6298
dc.identifier.doi10.1158/0008-5472.can-17-0976
dc.identifier.issn0008-5472
dc.identifier.issn1538-7445
dc.identifier.orcidSelth, L. [0000-0002-4686-1418]
dc.identifier.orcidTilley, W. [0000-0003-1893-2626]
dc.identifier.urihttp://hdl.handle.net/2440/119732
dc.language.isoen
dc.publisherAmerican Association for Cancer Research
dc.rights© 2017 American Association for Cancer Research.
dc.source.urihttps://doi.org/10.1158/0008-5472.can-17-0976
dc.subjectCell Line, Tumor
dc.subjectAnimals
dc.subjectMice, Inbred NOD
dc.subjectMice, Knockout
dc.subjectHumans
dc.subjectMice, SCID
dc.subjectAnilides
dc.subjectIndoles
dc.subjectReceptors, Androgen
dc.subjectXenograft Model Antitumor Assays
dc.subjectGene Expression Profiling
dc.subjectCell Proliferation
dc.subjectGene Expression Regulation, Neoplastic
dc.subjectAlternative Splicing
dc.subjectMolecular Structure
dc.subjectMale
dc.subjectAndrogen Receptor Antagonists
dc.subjectProstatic Neoplasms, Castration-Resistant
dc.titleNovel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancer
dc.typeJournal article
pubs.publication-statusPublished

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