Systematic investigation of gastrointestinal diseases in China (SILC): validation of survey methodology

dc.contributor.authorYan, X.
dc.contributor.authorWang, R.
dc.contributor.authorZhao, Y.
dc.contributor.authorMa, X.
dc.contributor.authorFang, J.
dc.contributor.authorYan, H.
dc.contributor.authorKang, X.
dc.contributor.authorYin, P.
dc.contributor.authorHao, Y.
dc.contributor.authorLi, Q.
dc.contributor.authorDent, J.
dc.contributor.authorSung, J.
dc.contributor.authorZou, D.
dc.contributor.authorJohansson, S.
dc.contributor.authorHalling, K.
dc.contributor.authorLiu, W.
dc.contributor.authorHe, J.
dc.date.issued2009
dc.description.abstractBackground: Symptom-based surveys suggest that the prevalence of gastrointestinal diseases is lower in China than in Western countries. The aim of this study was to validate a methodology for the epidemiological investigation of gastrointestinal symptoms and endoscopic findings in China. Methods: A randomized, stratified, multi-stage sampling methodology was used to select 18 000 adults aged 18-80 years from Shanghai, Beijing, Xi'an, Wuhan and Guangzhou. Participants from Shanghai were invited to provide blood samples and undergo upper gastrointestinal endoscopy. All participants completed Chinese versions of the Reflux Disease Questionnaire (RDQ) and the modified Rome II questionnaire; 20% were also invited to complete the 36-item Short Form Health Survey (SF-36) and Epworth Sleepiness Scale (ESS). The psychometric properties of the questionnaires were evaluated statistically. Results: The study was completed by 16 091 individuals (response rate: 89.4%), with 3219 (89.4% of those invited) completing the SF-36 and ESS. All 3153 participants in Shanghai provided blood samples and 1030 (32.7%) underwent endoscopy. Cronbach's alpha coefficients were 0.89, 0.89, 0.80 and 0.91, respectively, for the RDQ, modified Rome II questionnaire, ESS and SF-36, supporting internal consistency. Factor analysis supported construct validity of all questionnaire dimensions except SF-36 psychosocial dimensions. Conclusion: This population-based study has great potential to characterize the relationship between gastrointestinal symptoms and endoscopic findings in China.
dc.description.statementofresponsibilityXiaoyan Yan, Rui Wang, Yanfang Zhao, Xiuqiang Ma, Jiqian Fang, Hong Yan, Xiaoping Kang, Ping Yin, Yuantao Hao, Qiang Li, John Dent, Joseph Sung, Duowu Zou, Saga Johansson, Katarina Halling, Wenbin Liu and Jia He
dc.identifier.citationBMC Gastroenterology, 2009; 9(1):86-1-86-13
dc.identifier.doi10.1186/1471-230X-9-86
dc.identifier.issn1471-230X
dc.identifier.issn1471-230X
dc.identifier.urihttp://hdl.handle.net/2440/58781
dc.language.isoen
dc.publisherBiomedcentral Ltd
dc.rights© 2009 Yan et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.source.urihttps://doi.org/10.1186/1471-230x-9-86
dc.subjectHumans
dc.subjectGastrointestinal Diseases
dc.subjectDiagnosis, Differential
dc.subjectEndoscopy, Gastrointestinal
dc.subjectBiopsy
dc.subjectPopulation Surveillance
dc.subjectPrevalence
dc.subjectRetrospective Studies
dc.subjectReproducibility of Results
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectMiddle Aged
dc.subjectChina
dc.subjectFemale
dc.subjectMale
dc.subjectYoung Adult
dc.subjectSurveys and Questionnaires
dc.titleSystematic investigation of gastrointestinal diseases in China (SILC): validation of survey methodology
dc.typeJournal article
pubs.publication-statusPublished

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