Physiological mechanisms underlying the control of meal size in Manduca sexta larvae

Date

1992

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Timmins, W.
Reynolds, S.

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Physiological Entomology, 1992; 17(1):81-89

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W. A. Timmins and S. E. Reynolds

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Abstract

Fifth stadium larvae of the tobacco hornworm, Manduca sexta (L.), ate larger meals than usual when they had been deprived of food for periods of time longer than the usual intermeal interval (c. 45 min). Meal size increased with time since the last meal until 180 min, when it was about 3 times normal. There was no evidence of a role for volumetric feedback from the gut in controlling meal size. Injections of a paraffin oil/wax mixture, or of petroleum jelly (Vaseline) into the foregut, midgut or rectum failed to decrease meal size. Cutting the recurrent nerve failed to alter meal size compared to sham-operated controls (although both groups took smaller meals than unoperated controls). By contrast, injections of an extract of soluble nutrients from the diet into the midgut inhibited feeding in some insects and reduced subsequent meal size in others. Appropriate controls showed that these effects were not due to the volumetric or osmotic effects of the injections. These results imply that nutrient feedback plays an important role in controlling meal size in Manduca caterpillars, while volumetric feedback is probably unimportant.

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