Current studentsExisting staffContact us
 

Metabolic syndrome and incident coronary heart disease in Australian indigenous populations

Simple item page
dc.contributor.authorLi, M.
dc.contributor.authorMcCulloch, B.
dc.contributor.authorMcDermott, R.
dc.date.issued2012
dc.description.abstractThis report aims to compare the prediction of the metabolic syndrome (MetS) and its components for morbidity and mortality of coronary heart disease (CHD) in a cohort of Australian Aboriginal and Torres Strait Islander adults (TSIs). A total of 2,100 adults (1,283 Aborigines and 817 TSIs) was followed up for 6 years from 2000. Outcome measures were all CHD events (deaths and hospitalizations). Baseline anthropometric measurements, blood pressure (BP), fasting blood lipids and glucose were collected. Smoking and alcohol intake was self-reported. We found MetS was more prevalent in TSI (50.3%) compared to Aborigines (33.0%). Baseline MetS doubled the risk of a CHD event in Aborigines. Increased fasting triglycerides was stronger in predicting CHD (hazard ratio (HR): 2.8) compared with MetS after adjusted for age, sex, tobacco and alcohol consumption, and baseline diabetes and albuminuria for Aborigines but not among TSIs. MetS was not more powerful than its components in predicting CHD event. In Australian Aborigines, the “triglyceridemic waist” phenotype strongly predicts CHD event, whereas among TSI, baseline diabetes mediated the prediction of increased fasting glucose for CHD event.
dc.identifier.citationObesity, 2012; 20(6):1308-1312
dc.identifier.doi10.1038/oby.2011.156
dc.identifier.issn1930-7381
dc.identifier.issn1930-739X
dc.identifier.urihttps://hdl.handle.net/1959.8/124002
dc.language.isoen
dc.publisherNature Publishing Group
dc.relation.fundingNHMRC 279402
dc.rightsCopyright 2012 The Obesity Society
dc.source.urihttps://doi.org/10.1038/oby.2011.156
dc.subjectmetabolic syndrome
dc.subjectheart disease
dc.subjectindigenous
dc.subjectfasting triglycerides
dc.subjectHumans
dc.subjectAlbuminuria
dc.subjectCoronary Disease
dc.subjectMetabolic Syndrome X
dc.subjectBlood Glucose
dc.subjectLipids
dc.subjectQuestionnaires
dc.subjectPrevalence
dc.subjectRisk Factors
dc.subjectCohort Studies
dc.subjectPredictive Value of Tests
dc.subjectAlcohol Drinking
dc.subjectSmoking
dc.subjectBlood Pressure
dc.subjectPhenotype
dc.subjectAdult
dc.subjectOceanic Ancestry Group
dc.subjectNorthern Territory
dc.subjectFemale
dc.subjectMale
dc.subjectWaist Circumference
dc.titleMetabolic syndrome and incident coronary heart disease in Australian indigenous populations
dc.typeJournal article
pubs.publication-statusPublished
ror.fileinfo12142893390001831 13142957640001831 9915914120601831_53109902200001831.pdf
ror.mmsid9915914120601831

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
9915914120601831_53109902200001831.pdf
Size:
740.55 KB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections