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First human case of fatal Halicephalobus gingivalis meningoencephalitis in Australia

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dc.contributor.authorLim, C.K.
dc.contributor.authorCrawford, A.
dc.contributor.authorMoore, C.V.
dc.contributor.authorGasser, R.B.
dc.contributor.authorNelson, R.
dc.contributor.authorKoehler, A.V.
dc.contributor.authorBradbury, R.S.
dc.contributor.authorSpeare, R.
dc.contributor.authorDhatrak, D.
dc.contributor.authorWeldhagen, G.F.
dc.contributor.editorGilligan, P.H.
dc.date.issued2015
dc.description.abstractHalicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses. Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H. gingivalis infection in an Australian human patient, confirmed by nematode morphology and sequencing of ribosomal DNA. The implications of this case are discussed, particularly, the need to evaluate real-time PCR as a diagnostic tool.
dc.description.statementofresponsibilityChuan Kok Lim, April Crawford, Casey V. Moore, Robin B. Gasser, Renjy Nelson, Anson V. Koehler, Richard S. Bradbury, Rick Speare, Deepak Dhatrak, Gerhard. F. Weldhagen
dc.identifier.citationJournal of Clinical Microbiology, 2015; 53(5):1768-1774
dc.identifier.doi10.1128/JCM.00032-15
dc.identifier.issn0095-1137
dc.identifier.issn1098-660X
dc.identifier.orcidNelson, R. [0000-0002-2051-5998]
dc.identifier.urihttp://hdl.handle.net/2440/91627
dc.language.isoen
dc.publisherAmerican Society for Microbiology
dc.rightsCopyright © 2015, American Society for Microbiology. All Rights Reserved.
dc.source.urihttps://doi.org/10.1128/jcm.00032-15
dc.subjectBrain
dc.subjectAnimals
dc.subjectHumans
dc.subjectRhabditida
dc.subjectRhabditida Infections
dc.subjectMeningoencephalitis
dc.subjectDNA, Ribosomal
dc.subjectMicroscopy
dc.subjectHistocytochemistry
dc.subjectSequence Analysis, DNA
dc.subjectMolecular Sequence Data
dc.subjectAged
dc.subjectAustralia
dc.subjectFemale
dc.titleFirst human case of fatal Halicephalobus gingivalis meningoencephalitis in Australia
dc.typeJournal article
pubs.publication-statusPublished

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