Optimising breastmilk feeding in preterm infants to improve clinical outcomes

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dc.contributor.advisorMiddleton, Phillipa
dc.contributor.advisorKeir, Amy
dc.contributor.advisorCollins, Carmel
dc.contributor.advisorGomersall, Judith
dc.contributor.authorHilditch, Catherine Elizabeth
dc.contributor.schoolAdelaide Medical Schoolen
dc.date.issued2023
dc.description.abstractThe World Health Organization (WHO) recommends exclusive breastfeeding for all infants from birth to six months of age1. Breastfed infants are less susceptible to inflammatory disorders2 and infection3. The nutritional requirements of preterm infants are higher than those of term infants4,5, and the recommended source of nutrition for premature infants is human milk fortified with added nutrients1,4. Additional benefits for preterm infants6 include promoting intestinal maturation, improved feed tolerance, reduced time to reach full enteral feeds and improved growth rates7,8. Sustained breastmilk feeding has also been shown to reduce the rates and severity of complications of prematurity9-11, including sepsis3, necrotising enterocolitis12,13, and bronchopulmonary dysplasia14. Despite these well described advantages, breastmilk alone provides insufficient quantities of protein, sodium, phosphate, and calcium required to meet the nutritional needs of a preterm infant15. Studies suggest premature infants fed only human milk have lower growth rates than infants fed preterm infant formula or fortified human milk5,15,16. Commercially produced human milk fortifiers are recommended to supplement breast milk with additional nutrients, vitamins, and minerals.en
dc.description.dissertationThesis (MClin.Sc) -- University of Adelaide, Adelaide Medical School, 2023en
dc.identifier.urihttps://hdl.handle.net/2440/140288
dc.language.isoenen
dc.provenanceThis electronic version is made publicly available by the University of Adelaide in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. This thesis may incorporate third party material which has been used by the author pursuant to Fair Dealing exceptions. If you are the owner of any included third party copyright material you wish to be removed from this electronic version, please complete the take down form located at: http://www.adelaide.edu.au/legalsen
dc.subjectBreastfeedingen
dc.subjectbreastmilk feedingen
dc.subjectpreterm infantsen
dc.subjectneonatal intensive care unitsen
dc.subjectbreastmilk fortificationen
dc.titleOptimising breastmilk feeding in preterm infants to improve clinical outcomesen
dc.typeThesisen

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