Risk factors for primary open-angle glaucoma in a Burmese population: the Meiktila Eye Study

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dc.contributor.authorCasson, R.
dc.contributor.authorGupta, A.
dc.contributor.authorNewland, H.
dc.contributor.authorMcGovern, S.
dc.contributor.authorMuecke, J.
dc.contributor.authorSelva-Nayagam, D.
dc.contributor.authorAung, T.
dc.date.issued2007
dc.descriptionThe definitive version is available at www.blackwell-synergy.com
dc.description.abstractPurpose: To report the risk factors associated with primary open-angle glaucoma (POAG) in the Burmese population. Methods: The Meiktila Eye study, a population-based cross-sectional study, included inhabitants 40 years of age and over from villages in the Meiktila District. Of 2481 eligible participants identified, 2076 participated in the study and sufficient examination data to diagnose glaucoma in at least one eye was obtained in 1997 participants. The ophthalmic examination included slit-lamp examination, tonometry, gonioscopy and dilated stereoscopic fundus examination. Definitions adhered to the International Society for Geographic and Epidemiological Ophthalmology's recommendations. Univariate and multivariate analyses of potential risk factors were performed. Results: The overall prevalence of POAG was 2.0% (95% CI 0.9–3.1). In the univariate analysis, increasing age (P = 0.024), spherical equivalent (P = 0.01), axial length (P = 0.023) and intraocular pressure (IOP; P < 0.001) were significantly associated with POAG. And in the multivariate analysis, myopia <0.5 D (P = 0.049), increasing age and IOP (P < 0.001) were significant risk factors for POAG. Conclusion: POAG in this Burmese population was associated with increasing age, axial myopia and IOP.
dc.description.statementofresponsibilityRobert J Casson, Aanchal Gupta, Henry S Newland, Steve McGovern, James Muecke, Dinesh Selva and Than Aung
dc.identifier.citationClinical and Experimental Ophthalmology, 2007; 35(8):739-744
dc.identifier.doi10.1111/j.1442-9071.2007.01619.x
dc.identifier.issn1442-6404
dc.identifier.issn1442-9071
dc.identifier.orcidCasson, R. [0000-0003-2822-4076]
dc.identifier.orcidSelva-Nayagam, D. [0000-0002-2169-5417]
dc.identifier.urihttp://hdl.handle.net/2440/44390
dc.language.isoen
dc.publisherBlackwell Publishing Asia
dc.source.urihttps://doi.org/10.1111/j.1442-9071.2007.01619.x
dc.subjectHumans
dc.subjectGlaucoma, Open-Angle
dc.subjectPrevalence
dc.subjectRisk Factors
dc.subjectCross-Sectional Studies
dc.subjectIntraocular Pressure
dc.subjectVisual Acuity
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectRural Population
dc.subjectMyanmar
dc.subjectFemale
dc.subjectMale
dc.titleRisk factors for primary open-angle glaucoma in a Burmese population: the Meiktila Eye Study
dc.typeJournal article
pubs.publication-statusPublished

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