Prediction of preeclampsia and delivery of small for gestational age babies based on a combination of clinical risk factors in high-risk women
Date
2011
Authors
Seed, Paul T.
Chappell, Lucy C.
Black, Michael A.
Poppe, Katrina K.
Hwang, Yuan-Chun
Kasabov, Nikola
McCowan, Lesley M. E.
Shennan, Andrew H.
Wu, Steven H.
Poston, Lucilla
Editors
Advisors
Journal Title
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Type:
Journal article
Citation
Hypertension in Pregnancy, 2011; 30(1):58-73
Statement of Responsibility
Paul T. Seed, Lucy C. Chappell, Michael A. Black, Katrina K. Poppe, Yuan-Chun Hwang, Nikola Kasabov, Lesley McCowan, Andrew H. Shennan, Steven H. Wu, Lucilla Poston, and Robyn A. North
Conference Name
Abstract
Objective. To develop clinical risk tools for preeclampsia and small for gestational age (SGA) in high-risk women.
Methods. Individual risk scores based on clinical risk factors were calculated using logistic regression and validated in 1687 women with obesity in first pregnancy, chronic hypertension, or previous preeclampsia.
Results. The risk of preeclampsia varied from 7% in obese primiparae without hypertension to 30% when previous preeclampsia and chronic hypertension occurred together. A prediction model incorporating these risk factors had a sensitivity of 48 and 89% for preeclampsia delivered <34 weeks' gestation.
Conclusion. Multiple clinical risk factors increase the risk of preeclampsia and SGA.
School/Discipline
School of Paediatrics and Reproductive Health : Obstetrics and Gynaecology
Dissertation Note
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