Antimicrobial Prescribing in a Regional Hospital: Impact on Prescribing Through Collaboration with an On-Site Clinical Pharmacy Service
Date
2022
Authors
Tantiongco, M.
Dettwiller, P.
Kowalski, S.
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Journal article
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Clinical Audit, 2022; Volume 14:31-39
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Abstract
Purpose: Antimicrobial stewardship programs are critical for promoting and monitoring judicious use of antimicrobials; however, there are many well-established barriers to their effective implementation in the rural setting. Pharmacist involvement in such programs is recommended as part of a multidisciplinary approach to improve appropriate antimicrobial prescribing. The aim of this study was to describe the impact of implementing a clinical pharmacy service on antimicrobial prescribing in a rural GP-led hospital; explore areas of suboptimal antimicrobial prescribing; and review the change in total antimicrobial cost per patient day.
Patients and Methods: A retrospective case series audit of pre- and post-implementation of a new clinical pharmacy service was undertaken. All adult patients who had presented with sepsis, cellulitis, urinary tract infections and pneumonia between May and August 2015 and repeated for the same months in 2018 were included. Appropriateness of therapy was assessed using the National Antimicrobial Prescribing Survey guidelines.
Results: A total of 115 antibiotic orders from 2015 and 158 orders from 2018 were included. During admission, 86% of the patients (55/64) in the post-intervention group were reviewed by a clinical pharmacist. Appropriate prescribing increased from 57% (66/115) in 2015 to 82% (129/158) in 2018 (P=0.001). Ceftriaxone was the most inappropriately prescribed antimicrobial. The cost of antimicrobial therapy was halved from $10.00 to $5.33 per patient day, pre- and post-implementation of a clinical pharmacy service, respectively.
Conclusion: The implementation of a clinical pharmacy service in a small rural GP-led hospital can significantly improve antimicrobial prescribing practices and provide considerable cost savings.
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Copyright 2022 The author(s). his work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. (http://creativecommons.org/licenses/by-nc/3.0/)