Aspirin use and early age-related macular degeneration: a meta-analysis

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dc.contributor.authorKahawita, S.
dc.contributor.authorCasson, R.
dc.date.issued2014
dc.description.abstractObjective: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). Methods: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). Results: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09–1.88). Conclusions: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.
dc.description.statementofresponsibilityShyalle K.Kahawita, Robert J.Casson
dc.identifier.citationCanadian Journal of Ophthalmology, 2014; 49(1):35-39
dc.identifier.doi10.1016/j.jcjo.2013.07.016
dc.identifier.issn0008-4182
dc.identifier.issn1715-3360
dc.identifier.orcidCasson, R. [0000-0003-2822-4076]
dc.identifier.urihttp://hdl.handle.net/2440/118712
dc.language.isoen
dc.publisherCanadian Ophthalmological Society
dc.rightsCrown Copyright © 2014 Published by Elsevier Inc on behalf of the Canadian Ophthalmological Society. All rights reserved.
dc.source.urihttps://doi.org/10.1016/j.jcjo.2013.07.016
dc.subjectPlatelet Aggregation Inhibitors
dc.titleAspirin use and early age-related macular degeneration: a meta-analysis
dc.typeJournal article
pubs.publication-statusPublished

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