Effects of vagal blockade on the complexity of heart rate variability in rats

dc.contributor.authorBaumert, M.
dc.contributor.authorNalivaiko, E.
dc.contributor.authorAbbott, D.
dc.contributor.conference11th Mediterranean Conference on Medical and Biomedical Engineering and Computing (MEDICON ) (26 Jun 2007 - 30 Jun 2007 : Ljubljana, Slovenia)
dc.contributor.editorJarm, T.
dc.contributor.editorKramar, P.
dc.contributor.editorZupanic, A.
dc.date.issued2007
dc.description.abstractIn this paper we investigate the influence of vagal blockage on heart rate variability complexity measures. Nine conscious rats are injected with methyl-scopolamine brobide (50 μg/kg s.c.). We analyze 10 minute segments of beat-to-beat intervals before and after injection by standard time and frequency domain methods, compression entropy, sample entropy, Poincaré plot, detrended fluctuation analysis and symbolic dynamics. All parameter domains show changes in heart rate variability after vagal blockade, indicating a decrease in heart rate complexity. In conclusion, vagal modulation plays an important role in the generation of heart complexity in rats or, in other words, heart rate complexity measures are sensitive to vagal heart rate modulation.
dc.description.statementofresponsibilityM. Baumert, E. Nalivaiko, and D. Abbott
dc.identifier.citationIFMBE proceedings, 2007 / Jarm, T., Kramar, P., Zupanic, A. (ed./s), vol.16, iss.1, pp.26-29
dc.identifier.doi10.1007/978-3-540-73044-6_8
dc.identifier.isbn9783540730439
dc.identifier.issn1680-0737
dc.identifier.issn1433-9277
dc.identifier.orcidBaumert, M. [0000-0003-2984-2167]
dc.identifier.orcidAbbott, D. [0000-0002-0945-2674]
dc.identifier.urihttp://hdl.handle.net/2440/44077
dc.language.isoen
dc.publisherSpringer-Verlag
dc.relation.granthttp://purl.org/au-research/grants/arc/DP0663345
dc.relation.ispartofseriesIFMBE Proceedings
dc.rights© Springer-Verlag Berlin Heidelberg 2007
dc.source.urihttps://doi.org/10.1007/978-3-540-73044-6_8
dc.subjectheart rate variability; complexity; vagal blockade; rat
dc.titleEffects of vagal blockade on the complexity of heart rate variability in rats
dc.typeConference paper
pubs.publication-statusPublished

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