Randomized controlled trial of laparoscopic anterior 180° partial versus posterior 270° partial fundoplication
| dc.contributor.author | Daud, W. | |
| dc.contributor.author | Thompson, S. | |
| dc.contributor.author | Jamieson, G. | |
| dc.contributor.author | Devitt, P. | |
| dc.contributor.author | Martin, I. | |
| dc.contributor.author | Watson, D. | |
| dc.date.issued | 2015 | |
| dc.description | Article first published online: 28 NOV 2013 | |
| dc.description.abstract | Background: Previous trials show good outcomes following anterior and posterior partial versus Nissen fundoplication for gastro-oesophageal reflux. However, it is unclear which partial fundoplication performs best. This study compared anterior 180° versus posterior 270° fundoplication. Methods: At three hospitals, patients were randomized to anterior 180° versus posterior 270° partial fundoplication, and clinical outcomes were determined using a structured questionnaire at 3, 6 and 12 months. Heartburn, dysphagia and satisfaction were assessed using 0–10 analoue scales, and adverse outcomes and side effects were determined. Endoscopy, manometry and pH monitoring were performed 6 months after surgery. Results: Forty-seven patients were randomized to anterior (n = 23) versus posterior (n = 24) fundoplication. Clinical outcomes for 93–98% of patients were available at each follow-up point. At 12 months, the mean heartburn score was higher following anterior fundoplication (2.7 versus 0.8, P = 0.045), although differences were not significant at earlier follow-up. Conversely, following posterior fundoplication, patients were less able to belch at 3 (56% versus 16%, P = 0.013) and 6 months (43% versus 9%, P = 0.017). No significant differences were demonstrated for dysphagia. Both groups had high rates of satisfaction with the outcome – 85% versus 86% satisfied at 12 months follow-up. Conclusion: Both partial fundoplications are effective treatments for gastro-oesophageal reflux. Posterior partial fundoplication is associated with less reflux symptoms offset by more side effects. | |
| dc.description.statementofresponsibility | Wan Najmi Wan Daud, Sarah K. Thompson, Glyn G. Jamieson, Peter G. Devitt, Ian J. G. Martin and David I. Watson | |
| dc.identifier.citation | ANZ Journal of Surgery, 2015; 85(9):668-672 | |
| dc.identifier.doi | 10.1111/ans.12476 | |
| dc.identifier.issn | 1445-1433 | |
| dc.identifier.issn | 1445-2197 | |
| dc.identifier.uri | http://hdl.handle.net/2440/87007 | |
| dc.language.iso | en | |
| dc.publisher | Wiley | |
| dc.rights | © 2013 Royal Australasian College of Surgeons | |
| dc.source.uri | https://doi.org/10.1111/ans.12476 | |
| dc.subject | Fundoplication; gastro-oesophageal reflux disease; laparoscopy; randomized controlled trial | |
| dc.title | Randomized controlled trial of laparoscopic anterior 180° partial versus posterior 270° partial fundoplication | |
| dc.title.alternative | Randomized controlled trial of laparoscopic anterior 180degrees partial versus posterior 270degrees partial fundoplication | |
| dc.type | Journal article | |
| pubs.publication-status | Published |